SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lfn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
(Lactobacillus
rhamnosus) 		5 / 11 THR A  93
ALA A  59
ASP A   2
ALA A  56
ASP A  31
 None
 1.32A 2admA-4lfnA:
undetectable		 2admA-4lfnA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.13A 2f9wA-4lfnA:
undetectable
2f9wB-4lfnA:
undetectable		 2f9wA-4lfnA:
28.47
2f9wB-4lfnA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		4 / 5 ILE B 141
LEU B 137
ASP A  63
ALA A  72
 None
 1.02A 2opxA-4lfnB:
3.8		 2opxA-4lfnB:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 10 GLY A  66
ASP A  63
ASP A  39
VAL A  41
LEU B  99
 None
 1.09A 3ay0B-4lfnA:
undetectable		 3ay0B-4lfnA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.19A 3bexC-4lfnA:
undetectable
3bexD-4lfnA:
undetectable		 3bexC-4lfnA:
22.31
3bexD-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 10 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.19A 3bexC-4lfnA:
undetectable
3bexD-4lfnA:
undetectable		 3bexC-4lfnA:
22.31
3bexD-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 10 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.19A 3bexE-4lfnA:
undetectable
3bexF-4lfnA:
undetectable		 3bexE-4lfnA:
22.31
3bexF-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.18A 3bexE-4lfnA:
undetectable
3bexF-4lfnA:
undetectable		 3bexE-4lfnA:
22.31
3bexF-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.16A 3bf1A-4lfnA:
undetectable
3bf1B-4lfnA:
undetectable		 3bf1A-4lfnA:
22.31
3bf1B-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.15A 3bf1A-4lfnA:
undetectable
3bf1B-4lfnA:
undetectable		 3bf1A-4lfnA:
22.31
3bf1B-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.17A 3bf1C-4lfnA:
undetectable
3bf1D-4lfnA:
undetectable		 3bf1C-4lfnA:
22.31
3bf1D-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.16A 3bf1C-4lfnA:
undetectable
3bf1D-4lfnA:
undetectable		 3bf1C-4lfnA:
22.31
3bf1D-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.20A 3bf1E-4lfnA:
undetectable
3bf1F-4lfnA:
undetectable		 3bf1E-4lfnA:
22.31
3bf1F-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 11 ASN A  88
VAL B 110
GLY B 107
ASP B  87
ILE B  69
 None
None
None
None
RBL  B 201 ( 4.7A)
 1.16A 3bf1E-4lfnA:
undetectable
3bf1F-4lfnA:
undetectable		 3bf1E-4lfnA:
22.31
3bf1F-4lfnA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 GLN B 151
PHE B 158
ASN B  78
VAL B  63
ILE B  81
 None
 1.23A 3claA-4lfnB:
undetectable		 3claA-4lfnB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 ILE B  62
ILE B   5
MET B  64
VAL B 120
ILE B 116
 None
 1.06A 3p4wB-4lfnB:
undetectable		 3p4wB-4lfnB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 10 ILE B  62
ILE B   5
MET B  64
VAL B 120
ILE B 116
 None
 1.06A 3p4wD-4lfnB:
undetectable		 3p4wD-4lfnB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 10 ILE B  62
ILE B   5
MET B  64
VAL B 120
ILE B 116
 None
 1.07A 3p4wE-4lfnB:
undetectable		 3p4wE-4lfnB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 11 GLN B 151
PHE B 158
ASN B  78
VAL B  63
ILE B  81
 None
 1.19A 4claA-4lfnB:
undetectable		 4claA-4lfnB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		4 / 8 ASP B  88
ASP A  63
ASP A   8
GLU A  85
 None
 1.10A 4feuD-4lfnB:
undetectable		 4feuD-4lfnB:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 GLY B   6
GLY B  33
SER B  19
VAL B  49
VAL B 103
 None
 1.00A 4htfB-4lfnB:
undetectable		 4htfB-4lfnB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 ILE B  81
ASP B  76
VAL A  41
ASP B 142
ILE B 141
 None
 1.35A 4i41A-4lfnB:
undetectable		 4i41A-4lfnB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 GLY B 107
ASP B   8
CYH B  65
GLY B  68
THR B  67
 None
RBL  B 201 (-3.0A)
RBL  B 201 (-3.4A)
None
RBL  B 201 (-3.4A)
 1.38A 4lb0A-4lfnB:
undetectable		 4lb0A-4lfnB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 VAL A  41
ILE A 102
VAL A  83
THR B  73
ALA A  72
 None
 1.28A 4oqrA-4lfnA:
undetectable		 4oqrA-4lfnA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 ASP B  87
THR A  81
ALA A  99
ASN A  97
CYH B  65
 None
None
None
RBL  B 201 (-2.7A)
RBL  B 201 (-3.4A)
 1.34A 4u15B-4lfnB:
undetectable		 4u15B-4lfnB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 GLY B 105
TYR B  42
TYR B 123
ALA B  92
ALA B  84
 None
RBL  B 201 (-4.1A)
None
None
None
 1.27A 4ymgA-4lfnB:
undetectable		 4ymgA-4lfnB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 12 GLY B 105
TYR B  42
TYR B 123
ALA B  92
ALA B  84
 None
RBL  B 201 (-4.1A)
None
None
None
 1.29A 4ymgB-4lfnB:
undetectable		 4ymgB-4lfnB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 6 ILE B  69
ALA A  90
THR A  89
VAL A  84
HIS A  91
 RBL  B 201 ( 4.7A)
None
None
None
None
 1.23A 5eclD-4lfnB:
undetectable		 5eclD-4lfnB:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		4 / 6 SER B  19
GLY B   6
ASN B   7
ILE B  30
 None
 1.05A 5j4nA-4lfnB:
undetectable		 5j4nA-4lfnB:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 9 TYR B  42
PRO B  43
ILE A 133
TRP B 165
TYR B  45
 RBL  B 201 (-4.1A)
None
None
None
None
 1.19A 5mvnC-4lfnB:
undetectable		 5mvnC-4lfnB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus) 		5 / 10 TYR B  42
PRO B  43
ILE A 133
TRP B 165
TYR B  45
 RBL  B 201 (-4.1A)
None
None
None
None
 1.20A 5mvnD-4lfnB:
undetectable		 5mvnD-4lfnB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.94A 5wz1A-4lfnB:
undetectable		 5wz1A-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.93A 5wz1C-4lfnB:
undetectable		 5wz1C-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.91A 5wz1D-4lfnB:
undetectable		 5wz1D-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.95A 5wz1E-4lfnB:
undetectable		 5wz1E-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.92A 5wz1F-4lfnB:
undetectable		 5wz1F-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.92A 5wz1G-4lfnB:
undetectable		 5wz1G-4lfnB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4lfn GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
A
GALACTOSE-6-PHOSPHAT
E ISOMERASE SUBUNIT
B
(Lactobacillus
rhamnosus;
Lactobacillus
rhamnosus) 		5 / 12 GLY B  46
GLY B  66
THR B  67
HIS A  96
ILE B  10
 None
RBL  B 201 (-3.4A)
RBL  B 201 (-3.4A)
RBL  B 201 (-3.7A)
RBL  B 201 (-4.1A)
 0.95A 5wz1H-4lfnB:
undetectable		 5wz1H-4lfnB:
19.06