SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lg3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		3 / 3 ALA A 102
VAL A 133
TRP A 139
 None
 0.76A 1micA-4lg3A:
undetectable
1micB-4lg3A:
undetectable		 1micA-4lg3A:
6.59
1micB-4lg3A:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		3 / 3 ASP A 176
ARG A 178
ASP A 172
 None
 0.73A 4fp9A-4lg3A:
undetectable		 4fp9A-4lg3A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		3 / 3 ASP A 176
ARG A 178
ASP A 172
 None
 0.65A 4fp9C-4lg3A:
undetectable		 4fp9C-4lg3A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		3 / 3 ASP A 176
ARG A 178
ASP A 172
 None
 0.63A 4fp9F-4lg3A:
undetectable		 4fp9F-4lg3A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		4 / 8 GLY A 150
ALA A 146
LYS A  81
GLU A 203
 None
 0.86A 4hyfC-4lg3A:
undetectable		 4hyfC-4lg3A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		4 / 7 THR A 107
LEU A 151
LYS A 157
GLU A  63
 None
None
None
SO4  A 302 ( 4.8A)
 1.12A 5tudA-4lg3A:
undetectable		 5tudA-4lg3A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		4 / 7 ALA A 124
THR A 125
TYR A 126
VAL A  88
 None
None
SO4  A 301 (-4.5A)
None
 0.92A 6cduA-4lg3A:
undetectable
6cduE-4lg3A:
undetectable		 6cduA-4lg3A:
22.71
6cduE-4lg3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		4 / 7 VAL A  88
ALA A 124
THR A 125
TYR A 126
 None
None
None
SO4  A 301 (-4.5A)
 0.93A 6cduH-4lg3A:
undetectable
6cduI-4lg3A:
undetectable		 6cduH-4lg3A:
22.71
6cduI-4lg3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4lg3 UNCHARACTERIZED
PROTEIN
(Desulfovibrio
piger) 		3 / 3 THR A 119
GLU A 177
ASN A 198
 None
EDO  A 305 ( 4.5A)
None
 0.86A 6nj9K-4lg3A:
undetectable		 6nj9K-4lg3A:
17.15