SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4lg6 ANKYRIN REPEAT
FAMILY A PROTEIN 2
(Homo
sapiens) 		5 / 12 SER A 270
LEU A 219
VAL A 241
ALA A 255
CYH A 223
 None
 1.25A 3u9fD-4lg6A:
undetectable
3u9fE-4lg6A:
undetectable		 3u9fD-4lg6A:
22.17
3u9fE-4lg6A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4lg6 ANKYRIN REPEAT
FAMILY A PROTEIN 2
(Homo
sapiens) 		5 / 12 SER A 270
LEU A 219
VAL A 241
ALA A 255
CYH A 223
 None
 1.27A 3u9fG-4lg6A:
undetectable
3u9fH-4lg6A:
undetectable		 3u9fG-4lg6A:
22.17
3u9fH-4lg6A:
22.17