SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lgi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_A_8MOA501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 11	VAL A 94 PHE A 90 ILE A 108 GLY A 106 LEU A 84	None	0.97A	1z11A-4lgiA: undetectable	1z11A-4lgiA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_B_8MOB501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 11	VAL A 94 PHE A 90 ILE A 108 GLY A 106 LEU A 84	None	0.98A	1z11B-4lgiA: undetectable	1z11B-4lgiA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA5_B_STRB302_1 (MINERALOCORTICOID RECEPTOR)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 12	LEU A 236 ASN A 240 ALA A 243 GLN A 246 SER A 171	None	1.42A	2aa5B-4lgiA: undetectable	2aa5B-4lgiA: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_B_ASDB1223_1 (GLUTATHIONE S-TRANSFERASE A2)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	4 / 8	ILE A 76 GLY A 77 LEU A 81 LEU A 84	None	0.87A	2vctB-4lgiA: undetectable	2vctB-4lgiA: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_D_SAMD301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 12	GLY A 77 ILE A 57 ASP A 82 ARG A 86 LEU A 81	None	1.25A	3iv6D-4lgiA: undetectable	3iv6D-4lgiA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_C_CGEC501_1 (CYTOCHROME P450 2B4)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 9	VAL A 189 ILE A 105 PHE A 90 THR A 79 VAL A 161	None	1.08A	3me6C-4lgiA: undetectable	3me6C-4lgiA: 21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3R_A_9PLA501_1 (CYTOCHROME P450 2A6)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 11	VAL A 94 PHE A 90 ILE A 108 GLY A 106 LEU A 84	None	1.02A	3t3rA-4lgiA: undetectable	3t3rA-4lgiA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_0 (WBDD)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 12	ILE A 182 ILE A 185 SER A 162 VAL A 161 ILE A 108	None	0.96A	4ax8A-4lgiA: undetectable	4ax8A-4lgiA: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZV_A_SAMA1474_0 (WBDD)	4lgi	UNCHARACTERIZED PROTEIN (Escherichia coli)	5 / 12	ILE A 182 ILE A 185 SER A 162 VAL A 161 ILE A 108	None	0.98A	4azvA-4lgiA: undetectable	4azvA-4lgiA: 19.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Z11_A_8MOA501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"VAL A  94;PHE A  90;ILE A 108;GLY A 106;LEU A  84","None","0.97A","1z11A-4lgiA:undetectable","1z11A-4lgiA:21.26"],["1Z11_B_8MOB501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"VAL A  94;PHE A  90;ILE A 108;GLY A 106;LEU A  84","None","0.98A","1z11B-4lgiA:undetectable","1z11B-4lgiA:21.26"],["2AA5_B_STRB302_1","MINERALOCORTICOID RECEPTOR","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"LEU A 236;ASN A 240;ALA A 243;GLN A 246;SER A 171","None","1.42A","2aa5B-4lgiA:undetectable","2aa5B-4lgiA:20.86"],["2VCT_B_ASDB1223_1","GLUTATHIONE S-TRANSFERASE A2","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",4,"ILE A  76;GLY A  77;LEU A  81;LEU A  84","None","0.87A","2vctB-4lgiA:undetectable","2vctB-4lgiA:19.76"],["3IV6_D_SAMD301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"GLY A  77;ILE A  57;ASP A  82;ARG A  86;LEU A  81","None","1.25A","3iv6D-4lgiA:undetectable","3iv6D-4lgiA:21.30"],["3ME6_C_CGEC501_1","CYTOCHROME P450 2B4","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"VAL A 189;ILE A 105;PHE A  90;THR A  79;VAL A 161","None","1.08A","3me6C-4lgiA:undetectable","3me6C-4lgiA:21.06"],["3T3R_A_9PLA501_1","CYTOCHROME P450 2A6","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"VAL A  94;PHE A  90;ILE A 108;GLY A 106;LEU A  84","None","1.02A","3t3rA-4lgiA:undetectable","3t3rA-4lgiA:21.26"],["4AX8_A_SAMA1474_0","WBDD","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"ILE A 182;ILE A 185;SER A 162;VAL A 161;ILE A 108","None","0.96A","4ax8A-4lgiA:undetectable","4ax8A-4lgiA:19.47"],["4AZV_A_SAMA1474_0","WBDD","4lgi","UNCHARACTERIZED PROTEIN","Escherichia coli",5,"ILE A 182;ILE A 185;SER A 162;VAL A 161;ILE A 108","None","0.98A","4azvA-4lgiA:undetectable","4azvA-4lgiA:19.47"]]