SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lgl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A 336
SER A 869
LEU A 873
GLY A 976
 None
 1.00A 1a4lB-4lglA:
undetectable		 1a4lB-4lglA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 771
ALA A 596
THR A 207
ILE A 770
 None
 0.77A 1c9sI-4lglA:
undetectable
1c9sJ-4lglA:
undetectable		 1c9sI-4lglA:
5.61
1c9sJ-4lglA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 771
ALA A 596
THR A 207
ILE A 770
 None
 0.77A 1c9sU-4lglA:
undetectable
1c9sV-4lglA:
undetectable		 1c9sU-4lglA:
5.61
1c9sV-4lglA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 THR A 867
GLU A 879
THR A 881
HIS A 732
 CME  A 974 ( 3.9A)
None
None
None
 1.31A 1d4fA-4lglA:
undetectable		 1d4fA-4lglA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 THR A 867
GLU A 879
THR A 881
HIS A 732
 CME  A 974 ( 3.9A)
None
None
None
 1.38A 1d4fB-4lglA:
undetectable		 1d4fB-4lglA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 THR A 867
GLU A 879
THR A 881
HIS A 732
 CME  A 974 ( 3.9A)
None
None
None
 1.30A 1d4fD-4lglA:
4.1		 1d4fD-4lglA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 9 LEU A 432
LEU A 393
VAL A 413
GLY A 412
ALA A 418
 None
 1.10A 1e7aA-4lglA:
undetectable		 1e7aA-4lglA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 539
TYR A 790
PHE A  33
 None
 0.91A 1eqbB-4lglA:
17.8		 1eqbB-4lglA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 539
TYR A 790
PHE A  33
 None
 0.92A 1eqbA-4lglA:
17.6		 1eqbA-4lglA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 539
TYR A 790
PHE A  33
 None
 0.92A 1eqbD-4lglA:
17.8		 1eqbD-4lglA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 539
TYR A 790
PHE A  33
 None
 0.93A 1eqbC-4lglA:
17.8		 1eqbC-4lglA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 GLY A 771
ALA A 596
THR A 207
ILE A 770
 None
 0.72A 1gtnA-4lglA:
undetectable
1gtnK-4lglA:
undetectable		 1gtnA-4lglA:
5.61
1gtnK-4lglA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 771
ALA A 596
THR A 207
ILE A 770
 None
 0.77A 1gtnE-4lglA:
undetectable
1gtnF-4lglA:
undetectable		 1gtnE-4lglA:
5.61
1gtnF-4lglA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 771
ALA A 596
THR A 207
ILE A 770
 None
 0.72A 1gtnI-4lglA:
undetectable
1gtnJ-4lglA:
undetectable		 1gtnI-4lglA:
5.61
1gtnJ-4lglA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A 322
SER A 323
ASN A 962
ASP A 325
 None
 0.98A 1hwiB-4lglA:
undetectable		 1hwiB-4lglA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 VAL A 322
SER A 323
ASN A 962
ASP A 325
 None
 1.01A 1hwiC-4lglA:
undetectable		 1hwiC-4lglA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 VAL A 322
SER A 323
ASN A 962
ASP A 325
 None
 1.00A 1hwiD-4lglA:
1.8		 1hwiD-4lglA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A 322
SER A 323
ASN A 962
ASP A 325
 None
 0.99A 1hwkA-4lglA:
1.9		 1hwkA-4lglA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A 322
SER A 323
ASN A 962
ASP A 325
 None
 0.98A 1hwkC-4lglA:
1.9		 1hwkC-4lglA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A 322
SER A 323
ASN A 962
ASP A 325
 None
 0.99A 1hwkD-4lglA:
undetectable		 1hwkD-4lglA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 10 ALA A 717
VAL A 669
ILE A 685
GLY A 683
PRO A 672
 None
 1.09A 1k6cA-4lglA:
undetectable		 1k6cA-4lglA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 TYR A 131
GLU A 594
ILE A 730
GLY A 733
 None
 1.15A 1maaB-4lglA:
2.0
1maaD-4lglA:
undetectable		 1maaB-4lglA:
20.70
1maaD-4lglA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A 968
ASP A 853
ASN A 920
 CME  A 974 ( 4.3A)
None
None
 0.81A 1nbhA-4lglA:
3.9		 1nbhA-4lglA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A 968
ASP A 853
ASN A 920
 CME  A 974 ( 4.3A)
None
None
 0.81A 1nbhD-4lglA:
2.9		 1nbhD-4lglA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 PHE A 305
ASN A 163
ILE A 352
GLY A 317
 None
 1.11A 1oniA-4lglA:
undetectable
1oniB-4lglA:
undetectable		 1oniA-4lglA:
9.91
1oniB-4lglA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 ALA A 302
LEU A 359
ILE A 293
SER A 287
 None
 1.00A 1sbrA-4lglA:
undetectable
1sbrB-4lglA:
undetectable		 1sbrA-4lglA:
12.50
1sbrB-4lglA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 ALA A 781
VAL A 785
TRP A 788
 None
 0.91A 1tkqA-4lglA:
undetectable		 1tkqA-4lglA:
2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 771
ALA A 596
THR A 207
ILE A 770
 None
 0.76A 1utdI-4lglA:
undetectable
1utdJ-4lglA:
undetectable		 1utdI-4lglA:
5.61
1utdJ-4lglA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.82A 1v54P-4lglA:
undetectable
1v54W-4lglA:
undetectable		 1v54P-4lglA:
13.79
1v54W-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLU A 446
THR A 447
LEU A 295
 None
 0.72A 1v8bC-4lglA:
4.3		 1v8bC-4lglA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 HIS A 721
ALA A 596
GLY A 738
GLY A 740
TYR A 131
 None
 1.01A 1x1aA-4lglA:
undetectable		 1x1aA-4lglA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 177
ASN A 210
GLN A 599
 None
 1.05A 1xoqB-4lglA:
undetectable		 1xoqB-4lglA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 TRP A 870
PRO A 871
ASN A 702
GLY A 676
 CME  A 974 ( 4.7A)
None
None
None
 0.98A 1zlqA-4lglA:
undetectable		 1zlqA-4lglA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A 966
GLU A 852
ASP A 967
 None
 0.70A 2b25B-4lglA:
2.5		 2b25B-4lglA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 371
LEU A 375
GLY A 292
ALA A 363
ALA A 360
 None
 0.96A 2bm9F-4lglA:
2.4		 2bm9F-4lglA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 671
ALA A  64
ILE A  61
ILE A 807
ALA A 705
 None
 0.96A 2bxcA-4lglA:
undetectable		 2bxcA-4lglA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 PRO A 777
THR A 755
PRO A 753
 None
 0.80A 2d55C-4lglA:
undetectable		 2d55C-4lglA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 THR A 111
PRO A 114
TYR A 366
 None
 0.88A 2dxrA-4lglA:
undetectable		 2dxrA-4lglA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.84A 2dyrP-4lglA:
undetectable
2dyrW-4lglA:
undetectable		 2dyrP-4lglA:
13.79
2dyrW-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.81A 2eikP-4lglA:
undetectable
2eikW-4lglA:
undetectable		 2eikP-4lglA:
13.79
2eikW-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.87A 2eilC-4lglA:
undetectable
2eilJ-4lglA:
undetectable		 2eilC-4lglA:
13.79
2eilJ-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.80A 2eimP-4lglA:
undetectable
2eimW-4lglA:
undetectable		 2eimP-4lglA:
13.79
2eimW-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 11 GLY A 242
SER A 443
THR A 240
HIS A 198
GLN A 200
 None
 1.36A 2hmaA-4lglA:
undetectable		 2hmaA-4lglA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A 143
ALA A 145
TRP A 127
LEU A 513
 None
 1.20A 2oaxA-4lglA:
undetectable		 2oaxA-4lglA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 SER A 529
ASP A 699
GLY A 700
ASN A 723
GLY A 590
 CME  A 974 ( 3.8A)
None
None
None
None
 0.86A 2pkkA-4lglA:
2.6		 2pkkA-4lglA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 SER A 529
ASP A 699
GLY A 700
ASN A 723
GLY A 590
 CME  A 974 ( 3.8A)
None
None
None
None
 0.86A 2pkmA-4lglA:
2.5		 2pkmA-4lglA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE A 861
TYR A 821
LEU A 838
VAL A 878
LEU A 918
 None
 1.17A 2prgB-4lglA:
undetectable		 2prgB-4lglA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A 433
GLN A 200
PRO A 199
 None
 1.01A 2qhfA-4lglA:
undetectable		 2qhfA-4lglA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 LEU A 570
LEU A 784
TRP A 788
ILE A 791
 None
 1.11A 2rlfB-4lglA:
undetectable
2rlfC-4lglA:
undetectable		 2rlfB-4lglA:
4.49
2rlfC-4lglA:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 HIS A 623
LYS A 726
TYR A 131
TYR A 134
 CME  A 974 ( 4.2A)
CME  A 974 ( 3.3A)
None
None
 1.21A 2vmyA-4lglA:
25.9
2vmyB-4lglA:
25.7		 2vmyA-4lglA:
17.65
2vmyB-4lglA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 TYR A 131
TYR A 134
HIS A 623
LYS A 726
 None
None
CME  A 974 ( 4.2A)
CME  A 974 ( 3.3A)
 1.12A 2vmyA-4lglA:
26.1
2vmyB-4lglA:
25.6		 2vmyA-4lglA:
17.65
2vmyB-4lglA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 171
ILE A 352
ASP A 168
SER A 774
 None
 1.00A 2xytE-4lglA:
undetectable		 2xytE-4lglA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 ALA A 713
GLY A 683
CYH A 686
HIS A 690
 None
 0.77A 2yldA-4lglA:
undetectable		 2yldA-4lglA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.83A 3asnP-4lglA:
undetectable
3asnW-4lglA:
undetectable		 3asnP-4lglA:
13.79
3asnW-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 LYS A 376
LEU A 375
PHE A 291
PHE A 497
 None
 0.84A 3asoP-4lglA:
undetectable
3asoW-4lglA:
undetectable		 3asoP-4lglA:
13.79
3asoW-4lglA:
4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 10 VAL A 357
ALA A 302
ILE A 293
ILE A 117
PRO A 114
 None
 1.26A 3clbD-4lglA:
undetectable		 3clbD-4lglA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 10 ALA A 802
VAL A 707
ALA A 792
ILE A 791
PHE A 728
 None
 1.20A 3fl9A-4lglA:
undetectable		 3fl9A-4lglA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
CYH A 893
PRO A 880
 None
 1.20A 3h52C-4lglA:
undetectable		 3h52C-4lglA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 896
CYH A 836
PRO A 526
 None
 0.88A 3h52C-4lglA:
undetectable		 3h52C-4lglA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 896
CYH A 836
PRO A 866
 None
 1.13A 3h52C-4lglA:
undetectable		 3h52C-4lglA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 10 VAL A 357
ALA A 302
ILE A 293
ILE A 117
PRO A 114
 None
 1.25A 3hbbD-4lglA:
undetectable		 3hbbD-4lglA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		6 / 12 LEU A 234
GLY A 317
ALA A 173
GLY A 170
LEU A 167
ILE A 352
 None
 1.35A 3ku1A-4lglA:
4.4		 3ku1A-4lglA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		6 / 12 LEU A 234
GLY A 317
ALA A 173
GLY A 170
LEU A 167
ILE A 352
 None
 1.32A 3ku1C-4lglA:
undetectable		 3ku1C-4lglA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 ARG A 101
LEU A 389
ILE A 421
PHE A 460
 None
 1.06A 3ln1C-4lglA:
2.6		 3ln1C-4lglA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 ARG A 101
LEU A 389
ILE A 421
PHE A 460
 None
 1.07A 3ln1D-4lglA:
2.4		 3ln1D-4lglA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 PRO A 619
SER A 621
ASN A 626
 None
CME  A 642 ( 2.7A)
None
 0.87A 3lslG-4lglA:
undetectable		 3lslG-4lglA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 9 GLY A 280
ALA A 281
ASP A 282
ILE A 283
LEU A 263
 None
 0.72A 3ogpB-4lglA:
undetectable		 3ogpB-4lglA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A 156
LEU A 375
GLY A 371
GLY A 367
 None
 0.82A 3si7C-4lglA:
undetectable
3si7D-4lglA:
0.9		 3si7C-4lglA:
13.96
3si7D-4lglA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 9 ARG A 248
LEU A 279
ALA A 265
ASP A 266
LEU A 156
 None
 1.44A 3wsjA-4lglA:
undetectable		 3wsjA-4lglA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 ALA A 713
GLY A 683
CYH A 686
HIS A 690
 None
 0.78A 3zwiA-4lglA:
undetectable		 3zwiA-4lglA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A 539
SER A 787
MET A 789
TRP A 788
 None
 1.15A 4capA-4lglA:
undetectable
4capB-4lglA:
undetectable		 4capA-4lglA:
19.09
4capB-4lglA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 4 ALA A 713
GLY A 683
CYH A 686
HIS A 690
 None
 0.78A 4cipA-4lglA:
undetectable		 4cipA-4lglA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 ARG A 428
ILE A 442
PHE A 460
LEU A 389
 None
 0.94A 4mmcA-4lglA:
0.0		 4mmcA-4lglA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 ASN A 402
ALA A 243
GLY A 242
ASP A 196
 None
 0.89A 4n48A-4lglA:
2.2		 4n48A-4lglA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 LYS A 308
ASN A 163
ASP A 282
 None
 0.83A 4o1eA-4lglA:
undetectable		 4o1eA-4lglA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 PRO A 842
LEU A 843
GLN A 904
 None
 0.68A 4pevB-4lglA:
6.5		 4pevB-4lglA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 LEU A 279
ILE A 251
LEU A 263
TYR A 237
 None
 0.97A 4w5nA-4lglA:
3.5		 4w5nA-4lglA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 ASP A 455
LEU A 456
LEU A 432
ARG A 428
ILE A 430
 None
 0.90A 4x1fA-4lglA:
undetectable		 4x1fA-4lglA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 ASP A 455
LEU A 456
LEU A 432
ARG A 428
ILE A 430
 None
 0.90A 4x1gA-4lglA:
undetectable		 4x1gA-4lglA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 LEU A 456
THR A 386
LEU A 389
THR A 408
 None
 0.90A 4z90A-4lglA:
undetectable
4z90B-4lglA:
undetectable
4z90C-4lglA:
undetectable
4z90D-4lglA:
undetectable
4z90E-4lglA:
undetectable		 4z90A-4lglA:
17.65
4z90B-4lglA:
17.65
4z90C-4lglA:
17.65
4z90D-4lglA:
17.65
4z90E-4lglA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 10 THR A 386
LEU A 389
THR A 408
LEU A 409
LEU A 456
 None
 1.03A 4z91A-4lglA:
undetectable
4z91B-4lglA:
undetectable
4z91C-4lglA:
undetectable
4z91D-4lglA:
1.2
4z91E-4lglA:
undetectable		 4z91A-4lglA:
17.65
4z91B-4lglA:
17.65
4z91C-4lglA:
17.65
4z91D-4lglA:
17.65
4z91E-4lglA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 11 TYR A 131
SER A 591
GLU A 975
THR A 132
GLY A 735
 None
 1.42A 4zjoD-4lglA:
2.1		 4zjoD-4lglA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 TYR A 247
ASP A 266
ALA A 265
TYR A 237
 None
 1.16A 4zz8A-4lglA:
undetectable		 4zz8A-4lglA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 ALA A 705
ARG A 826
GLY A 827
GLU A 830
 None
 0.90A 5btgA-4lglA:
2.5
5btgB-4lglA:
undetectable
5btgC-4lglA:
2.5		 5btgA-4lglA:
21.85
5btgB-4lglA:
12.92
5btgC-4lglA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 7 ALA A 705
ARG A 826
GLY A 827
GLU A 830
 None
 0.93A 5btgA-4lglA:
2.5
5btgC-4lglA:
2.5
5btgD-4lglA:
undetectable		 5btgA-4lglA:
21.85
5btgC-4lglA:
21.85
5btgD-4lglA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 TYR A 821
LEU A 858
PRO A 866
LEU A 918
 None
 1.45A 5eshA-4lglA:
undetectable		 5eshA-4lglA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
GLN A  47
ARG A  46
 None
 0.88A 5ewzB-4lglA:
undetectable		 5ewzB-4lglA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 577
GLU A 576
MET A 794
GLU A 539
CYH A 729
 None
 1.48A 5fhzD-4lglA:
undetectable		 5fhzD-4lglA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 11 PRO A 267
LEU A 156
TYR A 366
LEU A 375
TYR A 491
 None
 1.48A 5hbmA-4lglA:
undetectable		 5hbmA-4lglA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 413
LEU A 456
ILE A 442
GLY A 412
TYR A 103
 None
 1.20A 5ienA-4lglA:
undetectable		 5ienA-4lglA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 4 ALA A 713
GLY A 683
CYH A 686
HIS A 690
 None
 0.76A 5jslA-4lglA:
undetectable		 5jslA-4lglA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
GLN A  47
ARG A  46
 None
 0.85A 5m35B-4lglA:
undetectable		 5m35B-4lglA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
GLN A  47
ARG A  46
 None
 0.88A 5m36A-4lglA:
undetectable		 5m36A-4lglA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 327
ASN A 329
ALA A 331
 None
 0.77A 5n4tB-4lglA:
2.1		 5n4tB-4lglA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 8 SER A 787
MET A 789
TRP A 788
GLU A 539
 None
 1.20A 5uo7A-4lglA:
undetectable
5uo7B-4lglA:
undetectable		 5uo7A-4lglA:
19.43
5uo7B-4lglA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLN A 768
ASP A 767
SER A 769
ARG A 754
 None
 1.39A 5w4zA-4lglA:
undetectable		 5w4zA-4lglA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A 733
VAL A 543
MET A 540
 None
 0.59A 5ycpA-4lglA:
undetectable		 5ycpA-4lglA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 590
GLY A 593
ASN A 723
THR A 354
TYR A 131
 None
 1.49A 5yf0A-4lglA:
4.3		 5yf0A-4lglA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 352
GLU A 594
GLY A 593
ALA A 589
ALA A 596
 None
 0.87A 5zw4A-4lglA:
undetectable		 5zw4A-4lglA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 730
GLY A 734
ALA A 139
ALA A 130
ALA A 519
 None
 1.02A 5zw4A-4lglA:
undetectable		 5zw4A-4lglA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 12 PRO A 199
ILE A 202
GLY A 170
ALA A 775
ALA A 776
 None
 1.06A 5zw4A-4lglA:
undetectable		 5zw4A-4lglA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 9 SER A 756
PHE A 554
SER A 780
GLY A 298
THR A 201
 None
 1.23A 6awpA-4lglA:
undetectable		 6awpA-4lglA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 9 ALA A 363
SER A 364
ALA A 302
ALA A 164
SER A 165
 None
 1.12A 6bklE-4lglA:
undetectable
6bklF-4lglA:
undetectable
6bklG-4lglA:
undetectable
6bklH-4lglA:
undetectable		 6bklE-4lglA:
2.79
6bklF-4lglA:
2.79
6bklG-4lglA:
2.79
6bklH-4lglA:
2.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 6 SER A 165
ALA A 363
SER A 364
ALA A 302
 None
 0.84A 6bocA-4lglA:
undetectable
6bocB-4lglA:
undetectable
6bocC-4lglA:
undetectable
6bocD-4lglA:
undetectable		 6bocA-4lglA:
2.79
6bocB-4lglA:
2.79
6bocC-4lglA:
2.79
6bocD-4lglA:
2.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 LYS A 550
VAL A  99
ASP A 110
 None
 0.71A 6fgdA-4lglA:
3.7		 6fgdA-4lglA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
GLN A  47
ARG A  46
 None
 0.86A 6fn9A-4lglA:
undetectable		 6fn9A-4lglA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
GLN A  47
ARG A  46
 None
 0.85A 6fnaB-4lglA:
undetectable		 6fnaB-4lglA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A  48
GLN A  47
ARG A  46
 None
 0.87A 6fnbA-4lglA:
undetectable		 6fnbA-4lglA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_1
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLN A 356
HIS A 301
TYR A 108
MET A 540
 None
 0.89A 6hlpA-4lglA:
2.8		 6hlpA-4lglA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 10 MET A 177
ALA A 176
TYR A 311
PHE A 305
VAL A 285
 None
 1.47A 6hu9C-4lglA:
undetectable		 6hu9C-4lglA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		3 / 3 THR A 129
GLU A 888
ASN A 521
 None
 0.64A 6nj9K-4lglA:
2.9		 6nj9K-4lglA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]
(Synechocystis
sp.
PCC
6803) 		5 / 9 ILE A 773
ALA A 596
GLY A 597
LEU A 598
GLY A 700
 None
 1.35A 6nm4B-4lglA:
undetectable		 6nm4B-4lglA:
11.55