SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4li3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 7 ILE X 234
ALA X 231
PRO X 235
LYS X 236
 None
 0.99A 1oniB-4li3X:
undetectable
1oniC-4li3X:
undetectable		 1oniB-4li3X:
19.75
1oniC-4li3X:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		6 / 10 LEU X 214
ALA X 201
ILE X 229
GLY X 177
GLY X 179
ILE X 210
 None
None
LLP  X  42 ( 4.7A)
LLP  X  42 ( 3.6A)
LLP  X  42 ( 3.5A)
None
 1.41A 1sdvA-4li3X:
undetectable		 1sdvA-4li3X:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		3 / 3 MET X  96
ASN X  72
GLN X 143
 None
LLP  X  42 ( 3.8A)
LLP  X  42 ( 4.9A)
 0.92A 1xoqB-4li3X:
undetectable		 1xoqB-4li3X:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 ILE X 229
LEU X 238
ALA X 201
GLU X 203
 LLP  X  42 ( 4.7A)
None
None
None
 1.27A 1xvaA-4li3X:
undetectable
1xvaB-4li3X:
undetectable		 1xvaA-4li3X:
23.36
1xvaB-4li3X:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 6 ALA X 201
GLU X 203
ILE X 229
LEU X 238
 None
None
LLP  X  42 ( 4.7A)
None
 1.02A 1xvaA-4li3X:
2.1
1xvaB-4li3X:
undetectable		 1xvaA-4li3X:
23.36
1xvaB-4li3X:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 VAL X 109
ILE X  75
GLY X  74
THR X  69
LEU X 111
 None
 1.03A 1z11A-4li3X:
undetectable		 1z11A-4li3X:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 VAL X 109
ILE X  75
GLY X  74
THR X  69
LEU X 111
 None
 1.04A 1z11B-4li3X:
undetectable		 1z11B-4li3X:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 10 VAL X 109
ILE X  75
GLY X  74
THR X  69
LEU X 111
 None
 1.08A 1z11C-4li3X:
undetectable		 1z11C-4li3X:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 10 VAL X 109
ILE X  75
GLY X  74
THR X  69
LEU X 111
 None
 1.00A 1z11D-4li3X:
undetectable		 1z11D-4li3X:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 GLU X 203
ALA X 201
PRO X 204
ALA X 279
ASP X 244
 None
 1.35A 2admA-4li3X:
undetectable		 2admA-4li3X:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.06A 2dcfA-4li3X:
undetectable		 2dcfA-4li3X:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 TYR X  79
ILE X  45
VAL X  80
ALA X  81
ILE X  65
 None
LLP  X  42 ( 4.0A)
None
None
None
 1.05A 2h42B-4li3X:
undetectable		 2h42B-4li3X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 TYR X  79
ILE X  45
VAL X  80
ALA X  81
ILE X  65
 None
LLP  X  42 ( 4.0A)
None
None
None
 1.04A 2h42C-4li3X:
undetectable		 2h42C-4li3X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 8 ILE X 161
ILE X 185
LYS X  31
GLU X  33
 None
 0.92A 2j9dJ-4li3X:
undetectable
2j9dK-4li3X:
undetectable
2j9dL-4li3X:
undetectable		 2j9dJ-4li3X:
20.14
2j9dK-4li3X:
20.14
2j9dL-4li3X:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 ILE X 234
ALA X 231
ILE X 210
SER X 181
ILE X 182
 None
None
None
LLP  X  42 ( 2.4A)
None
 0.97A 2w9sA-4li3X:
2.7		 2w9sA-4li3X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 ILE X 234
ALA X 231
ILE X 210
SER X 181
ILE X 182
 None
None
None
LLP  X  42 ( 2.4A)
None
 0.96A 2w9sB-4li3X:
2.7		 2w9sB-4li3X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 10 ILE X 234
ALA X 231
ILE X 210
SER X 181
ILE X 182
 None
None
None
LLP  X  42 ( 2.4A)
None
 0.94A 2w9sC-4li3X:
2.7		 2w9sC-4li3X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.04A 2zmaA-4li3X:
undetectable		 2zmaA-4li3X:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.08A 3a65A-4li3X:
undetectable		 3a65A-4li3X:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A66_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 10 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.06A 3a66A-4li3X:
0.0		 3a66A-4li3X:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.19A 3bjwA-4li3X:
undetectable		 3bjwA-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.16A 3bjwG-4li3X:
undetectable		 3bjwG-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.15A 3bjwC-4li3X:
undetectable		 3bjwC-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 VAL X 172
VAL X 173
THR X 157
THR X 198
 None
 1.23A 3bjwD-4li3X:
undetectable		 3bjwD-4li3X:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		3 / 3 ASN X  13
ASN X  36
GLU X  33
 None
 0.89A 3kpdB-4li3X:
undetectable		 3kpdB-4li3X:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 GLY X 230
GLU X 203
GLY X 232
PRO X 204
 None
 1.05A 3onnA-4li3X:
undetectable		 3onnA-4li3X:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 GLY X 158
ILE X  45
GLY X 180
ILE X 182
PRO X 299
 None
LLP  X  42 ( 4.0A)
LLP  X  42 ( 4.0A)
None
LLP  X  42 ( 4.0A)
 1.02A 3oxcB-4li3X:
undetectable		 3oxcB-4li3X:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 7 ASN X 146
ALA X 148
ARG X  84
ALA X  53
 None
 1.06A 3twpA-4li3X:
undetectable		 3twpA-4li3X:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWP_A_ACAA503_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 10 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.05A 3vwpA-4li3X:
undetectable		 3vwpA-4li3X:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.06A 3vwqA-4li3X:
undetectable		 3vwqA-4li3X:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 11 ALA X  76
SER X  40
ASN X  72
GLY X  46
ILE X  45
 LLP  X  42 ( 3.2A)
LLP  X  42 ( 3.0A)
LLP  X  42 ( 3.8A)
LLP  X  42 ( 3.7A)
LLP  X  42 ( 4.0A)
 1.05A 3vwrA-4li3X:
undetectable		 3vwrA-4li3X:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 9 ILE X  88
LEU X  90
PRO X  37
SER X  10
GLY X  46
 None
None
None
None
LLP  X  42 ( 3.7A)
 1.30A 3w1wB-4li3X:
2.1		 3w1wB-4li3X:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 LEU X 104
ILE X  75
ALA X  76
ALA X  81
GLY X  85
 None
None
LLP  X  42 ( 3.2A)
None
None
 1.14A 4enhA-4li3X:
undetectable		 4enhA-4li3X:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 ILE X 229
VAL X 219
SER X 207
LEU X 240
LEU X 238
 LLP  X  42 ( 4.7A)
None
None
None
None
 1.48A 4qztA-4li3X:
undetectable		 4qztA-4li3X:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 4 GLU X 160
GLY X 158
HIS X 153
ARG X  44
 None
 1.19A 4r82A-4li3X:
undetectable
4r82B-4li3X:
undetectable		 4r82A-4li3X:
21.45
4r82B-4li3X:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 5 GLU X  94
THR X  95
THR X  69
LEU X 104
 None
 1.27A 5axaA-4li3X:
2.9		 5axaA-4li3X:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 ALA X  76
THR X 156
ILE X  45
SER X 181
ASN X  36
 LLP  X  42 ( 3.2A)
None
LLP  X  42 ( 4.0A)
LLP  X  42 ( 2.4A)
None
 1.33A 5hgcA-4li3X:
undetectable		 5hgcA-4li3X:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 12 ILE X 229
GLY X 175
HIS X 224
ILE X 234
PHE X 233
 LLP  X  42 ( 4.7A)
None
None
None
None
 1.18A 5igwA-4li3X:
undetectable		 5igwA-4li3X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 6 GLU X 264
LEU X 261
ARG X 259
ARG X 260
 None
 1.23A 5l6eA-4li3X:
undetectable
5l6eB-4li3X:
undetectable		 5l6eA-4li3X:
22.26
5l6eB-4li3X:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 4 GLU X  94
THR X  95
THR X  69
LEU X 104
 None
 1.30A 5v96A-4li3X:
3.6		 5v96A-4li3X:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 4 GLU X  94
THR X  95
THR X  69
LEU X 104
 None
 1.29A 5v96C-4li3X:
3.6		 5v96C-4li3X:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		4 / 4 GLU X  94
THR X  95
THR X  69
LEU X 104
 None
 1.29A 5v96D-4li3X:
3.6		 5v96D-4li3X:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		3 / 3 THR X  14
GLU X 160
HIS X 153
 None
 0.88A 5xioA-4li3X:
undetectable		 5xioA-4li3X:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		3 / 3 THR X  14
GLU X 160
HIS X 153
 None
 0.89A 5xiqB-4li3X:
undetectable		 5xiqB-4li3X:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		3 / 3 THR X  14
GLU X 160
HIS X 153
 None
 0.90A 5xiqD-4li3X:
undetectable		 5xiqD-4li3X:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 4li3 CYSTEINE SYNTHASE
(Haemophilus
influenzae) 		5 / 10 ALA X  76
LEU X  77
VAL X  80
ALA X  53
ALA X 148
 LLP  X  42 ( 3.2A)
None
None
None
None
 1.09A 6h1lA-4li3X:
undetectable		 6h1lA-4li3X:
20.79