SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 TRP A  31
ALA A 381
VAL A 383
 None
 0.90A 1c4dC-4limA:
undetectable
1c4dD-4limA:
undetectable		 1c4dC-4limA:
5.69
1c4dD-4limA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 329
PHE A 379
ALA A 327
PHE A  80
 None
 1.08A 1fxvA-4limA:
undetectable
1fxvB-4limA:
undetectable		 1fxvA-4limA:
21.07
1fxvB-4limA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 381
VAL A 383
TRP A  31
 None
 0.94A 1tkqB-4limA:
undetectable		 1tkqB-4limA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 190
TYR A 310
ILE A 143
 None
 0.77A 3eteA-4limA:
undetectable
3eteB-4limA:
undetectable		 3eteA-4limA:
23.08
3eteB-4limA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 166
ASP A 113
ARG A 164
MET A  15
 None
 1.28A 3qx3A-4limA:
undetectable		 3qx3A-4limA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 10 HIS A 212
VAL A 191
PHE A 110
LEU A 148
THR A 146
 None
 1.34A 3zncA-4limA:
undetectable		 3zncA-4limA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 229
ASP A 278
GLU A 272
ALA A 241
 None
 0.98A 4nkxA-4limA:
undetectable		 4nkxA-4limA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 245
MET A 307
TYR A 250
 None
 0.91A 4p6xG-4limA:
undetectable		 4p6xG-4limA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 202
ALA A 204
LEU A 203
PHE A 152
 None
 0.84A 4rkuA-4limA:
undetectable
4rkuJ-4limA:
undetectable		 4rkuA-4limA:
19.11
4rkuJ-4limA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 167
TRP A 159
VAL A 160
 None
 0.12A 4w9nC-4limA:
undetectable		 4w9nC-4limA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 173
VAL A 171
THR A 144
ALA A 147
TRP A 159
 None
 1.35A 4yhaA-4limA:
undetectable		 4yhaA-4limA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 173
VAL A 171
THR A 144
ALA A 147
TRP A 159
 None
 1.40A 4yhaF-4limA:
undetectable		 4yhaF-4limA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 9 ASP A 314
ASP A 111
ILE A 112
ILE A 194
THR A 144
 None
 1.06A 5kr2A-4limA:
undetectable		 5kr2A-4limA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 6 ARG A  58
LYS A  57
PHE A  80
LEU A 324
 None
 1.14A 5x19P-4limA:
undetectable		 5x19P-4limA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 213
TYR A 310
LEU A 313
LEU A 148
ALA A 147
 None
 1.16A 5y7pB-4limA:
undetectable		 5y7pB-4limA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 166
ASP A 113
ARG A 164
MET A  15
 None
 1.34A 5zrfB-4limA:
undetectable		 5zrfB-4limA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 4 GLY A 166
ASP A 113
ARG A 164
MET A  15
 None
 1.32A 5zrfA-4limA:
1.8		 5zrfA-4limA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4lim DNA PRIMASE SMALL
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 6 ARG A  58
LYS A  57
PHE A  80
LEU A 324
 None
 1.22A 6nmpC-4limA:
undetectable
6nmpJ-4limA:
undetectable		 6nmpC-4limA:
20.96
6nmpJ-4limA:
10.06