SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4liy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 VAL A 269
VAL A 271
TRP A 290
 None
 0.96A 1av2A-4liyA:
undetectable
1av2B-4liyA:
undetectable		 1av2A-4liyA:
5.09
1av2B-4liyA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 8 THR A 307
LEU A 305
VAL A 180
VAL A 193
 None
 1.15A 1uyuB-4liyA:
undetectable		 1uyuB-4liyA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 ASN A 192
THR A 270
VAL A 271
VAL A 189
LEU A 183
 None
 1.38A 3elzC-4liyA:
undetectable		 3elzC-4liyA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 ASN A 142
ALA A 141
LYS A 155
 None
 0.92A 3runA-4liyA:
undetectable		 3runA-4liyA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 THR A 132
ASN A 131
GLU A 217
 None
 0.61A 3v4tA-4liyA:
undetectable
3v4tC-4liyA:
undetectable		 3v4tA-4liyA:
22.25
3v4tC-4liyA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 271
PHE A 312
SER A 313
LEU A 160
VAL A 161
 None
 1.18A 4eckA-4liyA:
undetectable		 4eckA-4liyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 TRP A 290
ILE A 145
SER A 154
 None
 0.96A 5gqbA-4liyA:
undetectable		 5gqbA-4liyA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 LEU A 158
LEU A 160
LEU A 210
ALA A 226
MET A 230
 None
 1.09A 5og9B-4liyA:
undetectable		 5og9B-4liyA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 LEU A 173
MET A 286
LEU A 210
ILE A 159
LEU A 214
 None
 1.04A 5toaA-4liyA:
undetectable		 5toaA-4liyA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 239
SER A 190
SER A 291
ASN A 192
TYR A 250
 None
 1.42A 6h7lA-4liyA:
undetectable		 6h7lA-4liyA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4liy FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 239
SER A 190
SER A 291
ASN A 192
TYR A 250
 None
 1.40A 6h7lB-4liyA:
undetectable		 6h7lB-4liyA:
15.92