SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I9G_A_SAMA301_0 (HYPOTHETICAL PROTEIN RV2118C)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	5 / 12	ILE A 121 GLY A 53 GLY A 132 SER A 65 ALA A 125	None	1.11A	1i9gA-4ljiA: undetectable	1i9gA-4ljiA: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	5 / 12	ALA A 72 LEU A 69 LEU A 82 PHE A 85 THR A 56	HEM A 301 ( 3.7A) HEM A 301 ( 4.8A) None HEM A 301 (-4.1A) HEM A 301 (-4.1A)	1.03A	2oipC-4ljiA: undetectable	2oipC-4ljiA: 12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_A_SAMA601_0 (HYPOTHETICAL PROTEIN)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	5 / 12	ILE A 121 GLY A 53 GLY A 132 SER A 65 ALA A 125	None	1.11A	2yvlA-4ljiA: undetectable	2yvlA-4ljiA: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_D_MTXD615_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	5 / 12	ALA A 72 LEU A 69 LEU A 82 PHE A 85 THR A 56	HEM A 301 ( 3.7A) HEM A 301 ( 4.8A) None HEM A 301 (-4.1A) HEM A 301 (-4.1A)	1.04A	3hj3D-4ljiA: undetectable	3hj3D-4ljiA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRI_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	4 / 5	GLY A 3 THR A 37 ILE A 9 VAL A 8	None	0.92A	3wriA-4ljiA: undetectable	3wriA-4ljiA: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRI_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	4 / 5	GLY A 3 THR A 37 ILE A 9 VAL A 8	None	0.92A	3wriB-4ljiA: undetectable	3wriB-4ljiA: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_B_NPSB602_1 (SERUM ALBUMIN)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	5 / 9	ALA A 124 LEU A 117 LEU A 36 LYS A 40 VAL A 8	None HEM A 301 ( 4.6A) None None None	1.04A	4or0B-4ljiA: undetectable	4or0B-4ljiA: 13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA503_1 (CYTOCHROME P450 2C9)	4lji	CYTOCHROME C-550-LIKE PROTEIN (Thermosynechococ cus elongatus)	5 / 12	ILE A 121 LEU A 57 PRO A 58 THR A 56 LEU A 64	None None HEM A 301 ( 4.4A) HEM A 301 (-4.1A) HEM A 301 (-4.9A)	1.27A	5xxiA-4ljiA: undetectable	5xxiA-4ljiA: 14.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1I9G_A_SAMA301_0","HYPOTHETICAL PROTEIN RV2118C","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",5,"ILE A 121;GLY A  53;GLY A 132;SER A  65;ALA A 125","None","1.11A","1i9gA-4ljiA:undetectable","1i9gA-4ljiA:17.86"],["2OIP_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",5,"ALA A  72;LEU A  69;LEU A  82;PHE A  85;THR A  56","HEM A 301 ( 3.7A);HEM A 301 ( 4.8A);None;HEM A 301 (-4.1A);HEM A 301 (-4.1A)","1.03A","2oipC-4ljiA:undetectable","2oipC-4ljiA:12.60"],["2YVL_A_SAMA601_0","HYPOTHETICAL PROTEIN","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",5,"ILE A 121;GLY A  53;GLY A 132;SER A  65;ALA A 125","None","1.11A","2yvlA-4ljiA:undetectable","2yvlA-4ljiA:17.34"],["3HJ3_D_MTXD615_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",5,"ALA A  72;LEU A  69;LEU A  82;PHE A  85;THR A  56","HEM A 301 ( 3.7A);HEM A 301 ( 4.8A);None;HEM A 301 (-4.1A);HEM A 301 (-4.1A)","1.04A","3hj3D-4ljiA:undetectable","3hj3D-4ljiA:14.81"],["3WRI_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",4,"GLY A   3;THR A  37;ILE A   9;VAL A   8","None","0.92A","3wriA-4ljiA:undetectable","3wriA-4ljiA:16.50"],["3WRI_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",4,"GLY A   3;THR A  37;ILE A   9;VAL A   8","None","0.92A","3wriB-4ljiA:undetectable","3wriB-4ljiA:16.50"],["4OR0_B_NPSB602_1","SERUM ALBUMIN","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",5,"ALA A 124;LEU A 117;LEU A  36;LYS A  40;VAL A   8","None;HEM A 301 ( 4.6A);None;None;None","1.04A","4or0B-4ljiA:undetectable","4or0B-4ljiA:13.55"],["5XXI_A_LSNA503_1","CYTOCHROME P450 2C9","4lji","CYTOCHROME C-550-LIKE PROTEIN","Thermosynechococcus elongatus",5,"ILE A 121;LEU A  57;PRO A  58;THR A  56;LEU A  64","None;None;HEM A 301 ( 4.4A);HEM A 301 (-4.1A);HEM A 301 (-4.9A)","1.27A","5xxiA-4ljiA:undetectable","5xxiA-4ljiA:14.94"]]