SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ljx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 4ljx AT-RICH INTERACTIVE
DOMAIN-CONTAINING
PROTEIN 3A
(Homo
sapiens) 		5 / 10 ILE A 289
ILE A 342
LEU A 338
ASN A 334
ASN A 290
 None
 1.18A 2nnhB-4ljxA:
undetectable		 2nnhB-4ljxA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 4ljx AT-RICH INTERACTIVE
DOMAIN-CONTAINING
PROTEIN 3A
(Homo
sapiens) 		4 / 4 TRP A 294
LEU A 275
LEU A 301
THR A 298
 None
 1.43A 4bboD-4ljxA:
undetectable		 4bboD-4ljxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4ljx AT-RICH INTERACTIVE
DOMAIN-CONTAINING
PROTEIN 3A
(Homo
sapiens) 		5 / 12 PHE A 249
PHE A 244
LEU A 270
ILE A 264
LEU A 232
 None
 1.00A 6aybA-4ljxA:
undetectable		 6aybA-4ljxA:
15.59