SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lkb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3003_1 (TRANSCRIPTIONAL REGULATOR TCAR)	4lkb	HYPOTHETICAL PROTEIN ALR4568/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE (Nostoc sp. PCC 7120)	4 / 6	ILE F 34 VAL F 2 HIS F 25 LEU F 24	None	0.79A	3kp6A-4lkbF: undetectable 3kp6B-4lkbF: undetectable	3kp6A-4lkbF: 24.56 3kp6B-4lkbF: 24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0P_A_TE4A201_1 (BETA-LACTOGLOBULIN)	4lkb	HYPOTHETICAL PROTEIN ALR4568/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE (Nostoc sp. PCC 7120)	5 / 12	VAL F 88 LEU F 103 ILE F 101 ILE F 64 ILE F 4	None	0.90A	4y0pA-4lkbF: undetectable	4y0pA-4lkbF: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JMN_B_FUAB1101_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	4lkb	HYPOTHETICAL PROTEIN ALR4568/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE (Nostoc sp. PCC 7120)	4 / 5	ILE F 99 LEU F 80 HIS F 41 VAL F 6	None	1.24A	5jmnB-4lkbF: 2.4	5jmnB-4lkbF: 9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEA_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	4lkb	HYPOTHETICAL PROTEIN ALR4568/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE (Nostoc sp. PCC 7120)	4 / 5	LEU F 81 LYS F 77 LEU F 103 GLU F 105	None	1.29A	5weaA-4lkbF: undetectable	5weaA-4lkbF: 11.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KP6_B_SALB3003_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","4lkb","HYPOTHETICAL PROTEIN ALR4568\/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE","Nostoc sp. PCC 7120",4,"ILE F  34;VAL F   2;HIS F  25;LEU F  24","None","0.79A","3kp6A-4lkbF:undetectable;3kp6B-4lkbF:undetectable","3kp6A-4lkbF:24.56;3kp6B-4lkbF:24.56"],["4Y0P_A_TE4A201_1","BETA-LACTOGLOBULIN","4lkb","HYPOTHETICAL PROTEIN ALR4568\/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE","Nostoc sp. PCC 7120",5,"VAL F  88;LEU F 103;ILE F 101;ILE F  64;ILE F   4","None","0.90A","4y0pA-4lkbF:undetectable","4y0pA-4lkbF:20.67"],["5JMN_B_FUAB1101_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","4lkb","HYPOTHETICAL PROTEIN ALR4568\/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE","Nostoc sp. PCC 7120",4,"ILE F  99;LEU F  80;HIS F  41;VAL F   6","None","1.24A","5jmnB-4lkbF:2.4","5jmnB-4lkbF:9.49"],["5WEA_A_IPHA901_0","PROTEIN ARGONAUTE-2","4lkb","HYPOTHETICAL PROTEIN ALR4568\/PUTATIVE 4-OXALOCROTONATE TAUTOMERASE","Nostoc sp. PCC 7120",4,"LEU F  81;LYS F  77;LEU F 103;GLU F 105","None","1.29A","5weaA-4lkbF:undetectable","5weaA-4lkbF:11.20"]]