SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lkr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 12 ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.37A 1jdvE-4lkrA:
34.2
1jdvF-4lkrA:
35.4		 1jdvE-4lkrA:
28.52
1jdvF-4lkrA:
28.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.59A 1odiA-4lkrA:
25.2		 1odiA-4lkrA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.60A 1odiB-4lkrA:
23.4		 1odiB-4lkrA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.55A 1odiC-4lkrA:
35.1		 1odiC-4lkrA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.59A 1odiD-4lkrA:
34.9		 1odiD-4lkrA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.61A 1odiE-4lkrA:
34.9		 1odiE-4lkrA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.59A 1odiF-4lkrA:
35.0		 1odiF-4lkrA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 9 MET A  64
ARG A  87
SER A  90
GLU A 181
SER A 203
ASP A 204
 None
 0.89A 1pk7A-4lkrA:
37.9		 1pk7A-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 9 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.43A 1pk7A-4lkrA:
37.9		 1pk7A-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 10 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.52A 1pk7C-4lkrA:
37.7		 1pk7C-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 10 MET A  64
ARG A  87
SER A  90
SER A 203
ASP A 204
 None
 1.03A 1pk7C-4lkrA:
37.7		 1pk7C-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 10 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.52A 1pk9A-4lkrA:
37.8		 1pk9A-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 9 MET A  64
ARG A  87
SER A  90
GLU A 181
SER A 203
ASP A 204
 None
 0.90A 1pk9B-4lkrA:
38.5		 1pk9B-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 9 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.45A 1pk9B-4lkrA:
38.5		 1pk9B-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.59A 1pk9C-4lkrA:
36.2		 1pk9C-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 10 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.45A 1pw7A-4lkrA:
37.8		 1pw7A-4lkrA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 10 MET A  64
ARG A  87
SER A  90
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
 0.85A 1pw7A-4lkrA:
37.8		 1pw7A-4lkrA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 9 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.37A 1pw7B-4lkrA:
38.3		 1pw7B-4lkrA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 9 MET A  64
SER A  90
GLU A 181
SER A 203
ASP A 204
 None
 0.99A 1pw7C-4lkrA:
37.8		 1pw7C-4lkrA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 9 MET A  64
SER A  90
MET A 180
GLU A 181
SER A 203
 None
 0.53A 1pw7C-4lkrA:
37.8		 1pw7C-4lkrA:
50.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.47A 1vhwA-4lkrA:
38.7
1vhwD-4lkrA:
38.8		 1vhwA-4lkrA:
49.61
1vhwD-4lkrA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 9 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.47A 1vhwB-4lkrA:
38.6
1vhwF-4lkrA:
38.1		 1vhwB-4lkrA:
49.61
1vhwF-4lkrA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.46A 1vhwC-4lkrA:
38.8
1vhwE-4lkrA:
38.8		 1vhwC-4lkrA:
49.61
1vhwE-4lkrA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.45A 1vhwA-4lkrA:
38.7
1vhwD-4lkrA:
38.8		 1vhwA-4lkrA:
49.61
1vhwD-4lkrA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.45A 1vhwC-4lkrA:
38.8
1vhwE-4lkrA:
38.8		 1vhwC-4lkrA:
49.61
1vhwE-4lkrA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 10 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.50A 1vhwB-4lkrA:
38.6
1vhwF-4lkrA:
38.1		 1vhwB-4lkrA:
49.61
1vhwF-4lkrA:
49.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 10 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.61A 1z35A-4lkrA:
36.9		 1z35A-4lkrA:
42.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 9 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.50A 1z37A-4lkrA:
37.0		 1z37A-4lkrA:
42.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
 None
 0.51A 2ac7A-4lkrA:
35.6
2ac7B-4lkrA:
35.7		 2ac7A-4lkrA:
47.27
2ac7B-4lkrA:
47.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
 None
 0.52A 2ac7A-4lkrA:
35.6
2ac7B-4lkrA:
35.7		 2ac7A-4lkrA:
47.27
2ac7B-4lkrA:
47.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		4 / 7 ILE A  77
ILE A  57
LEU A 188
LEU A 133
 None
 0.89A 3adxA-4lkrA:
undetectable		 3adxA-4lkrA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		4 / 6 GLY A 156
TYR A 159
GLY A  65
MET A  64
 None
 1.10A 3e9rA-4lkrA:
20.1		 3e9rA-4lkrA:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		4 / 6 GLY A 156
TYR A 159
GLY A  65
MET A  64
 None
 1.05A 3e9rC-4lkrA:
19.7		 3e9rC-4lkrA:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 10 ALA A 109
ILE A  88
LEU A 200
THR A 127
ILE A 194
 None
 1.16A 3prsA-4lkrA:
undetectable		 3prsA-4lkrA:
23.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 9 MET A  64
ARG A  87
SER A  90
MET A 180
GLU A 181
 None
 0.52A 3u40A-4lkrA:
35.7
3u40F-4lkrA:
34.9		 3u40A-4lkrA:
42.57
3u40F-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 10 MET A  64
ARG A  87
SER A  90
MET A 180
GLU A 181
CYH A 206
 None
 0.53A 3u40B-4lkrA:
35.5
3u40C-4lkrA:
35.2		 3u40B-4lkrA:
42.57
3u40C-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 12 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
CYH A 206
 None
 0.59A 3u40B-4lkrA:
35.5
3u40C-4lkrA:
35.2		 3u40B-4lkrA:
42.57
3u40C-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.47A 3u40D-4lkrA:
35.6
3u40E-4lkrA:
34.9		 3u40D-4lkrA:
42.57
3u40E-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 12 ARG A  24
ARG A  87
SER A  90
GLY A  92
CYH A 206
 None
 1.38A 3u40D-4lkrA:
35.6
3u40E-4lkrA:
34.9		 3u40D-4lkrA:
42.57
3u40E-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 12 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
CYH A 206
 None
 0.57A 3u40D-4lkrA:
35.6
3u40E-4lkrA:
34.9		 3u40D-4lkrA:
42.57
3u40E-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 10 MET A  64
ARG A  87
SER A  90
MET A 180
GLU A 181
 None
 0.47A 3u40A-4lkrA:
35.7
3u40F-4lkrA:
34.9		 3u40A-4lkrA:
42.57
3u40F-4lkrA:
42.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 11 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.58A 3uawA-4lkrA:
36.8		 3uawA-4lkrA:
47.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 10 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
 None
 0.47A 3uayA-4lkrA:
37.2		 3uayA-4lkrA:
46.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		8 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
 0.75A 4d9hA-4lkrA:
37.5		 4d9hA-4lkrA:
49.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 9 MET A  64
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
 0.85A 4da6A-4lkrA:
37.6		 4da6A-4lkrA:
49.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 10 MET A  64
ARG A  87
GLY A  92
MET A 180
GLU A 181
SER A 203
 None
 0.48A 4da7A-4lkrA:
37.5		 4da7A-4lkrA:
49.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		8 / 11 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
 0.75A 4danA-4lkrA:
37.3		 4danA-4lkrA:
49.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 12 ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
 0.77A 4danA-4lkrA:
37.3
4danB-4lkrA:
37.5		 4danA-4lkrA:
49.43
4danB-4lkrA:
49.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		4 / 5 LEU A 197
SER A 132
LEU A 105
ASN A 234
 None
 1.28A 4n09B-4lkrA:
undetectable		 4n09B-4lkrA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 10 ALA A 106
GLY A 187
GLY A 184
ALA A 183
ASP A 179
SER A 155
 None
 1.17A 4qvmY-4lkrA:
undetectable
4qvmZ-4lkrA:
undetectable		 4qvmY-4lkrA:
22.22
4qvmZ-4lkrA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 12 VAL A  70
GLY A 187
ALA A 189
ILE A  77
VAL A  82
 None
 0.98A 4xdrA-4lkrA:
undetectable		 4xdrA-4lkrA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 12 MET A  45
VAL A  42
GLU A  75
ILE A  77
ILE A  85
 None
 1.47A 4xucA-4lkrA:
undetectable		 4xucA-4lkrA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 12 MET A  45
VAL A  42
GLU A  75
ILE A  77
ILE A  85
 None
 1.49A 4xudA-4lkrA:
undetectable		 4xudA-4lkrA:
22.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		6 / 9 MET A  64
ARG A  87
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.52A 5i3cA-4lkrA:
38.2		 5i3cA-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 10 MET A  64
GLY A  92
MET A 180
GLU A 181
ASP A 204
 None
 0.77A 5i3cB-4lkrA:
20.4		 5i3cB-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		5 / 10 MET A  64
SER A  90
GLY A  92
MET A 180
GLU A 181
 None
 0.64A 5i3cB-4lkrA:
20.4		 5i3cB-4lkrA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		7 / 11 MET A  64
SER A  90
GLY A  92
MET A 180
GLU A 181
SER A 203
ASP A 204
 None
 0.82A 5i3cC-4lkrA:
38.2		 5i3cC-4lkrA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4lkr PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Shewanella
oneidensis) 		4 / 7 ALA A 169
ASP A 179
ILE A 178
ASP A 161
 None
 0.89A 6fbnA-4lkrA:
undetectable		 6fbnA-4lkrA:
22.60