SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ll1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		4 / 4 LEU A 234
LEU A 294
SER A 275
LEU A 277
 None
 1.14A 1ya3A-4ll1A:
undetectable		 1ya3A-4ll1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		3 / 3 GLN A 232
THR A 231
LEU A 294
 None
 0.76A 3ondB-4ll1A:
undetectable		 3ondB-4ll1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 102
ILE A  46
ALA A  48
PHE A 143
VAL A 125
 None
 1.12A 4u8vB-4ll1A:
undetectable		 4u8vB-4ll1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 102
ILE A  46
ALA A  48
PHE A 143
VAL A 125
 None
 1.12A 4u8yB-4ll1A:
undetectable		 4u8yB-4ll1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		4 / 7 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.19A 5bphB-4ll1A:
undetectable		 5bphB-4ll1A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 123
GLY A 108
SER A  23
LEU A 105
 None
 1.18A 5bphD-4ll1A:
undetectable		 5bphD-4ll1A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4ll1 THIOREDOXIN-INTERACT
ING PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 278
VAL A 237
PRO A 211
ALA A 213
 None
 0.89A 5cu6A-4ll1A:
undetectable		 5cu6A-4ll1A:
20.67