SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lla'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M4I_A_KANA500_1 (AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE)	4lla	LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2 (Homo sapiens)	4 / 8	GLY A 101 SER A 181 THR A 135 ASP A 185	None	0.78A	1m4iA-4llaA: undetectable	1m4iA-4llaA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_E_ACTE503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	4lla	LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2 (Homo sapiens)	3 / 3	GLN A 26 THR A 64 ASN A 62	None	0.85A	3v4tE-4llaA: undetectable	3v4tE-4llaA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKB_A_198A1002_2 (ANDROGEN RECEPTOR)	4lla	LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2 (Homo sapiens)	4 / 6	LEU A 196 MET A 165 LEU A 138 VAL A 16	None	0.89A	4okbA-4llaA: undetectable	4okbA-4llaA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KF8_A_GCSA404_1 (PREDICTED ACETYLTRANSFERASE)	4lla	LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2 (Homo sapiens)	4 / 8	ARG A 77 GLU A 41 GLY A 74 ASP A 96	None	1.08A	5kf8A-4llaA: undetectable	5kf8A-4llaA: 18.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1M4I_A_KANA500_1","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","4lla","LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2","Homo sapiens",4,"GLY A 101;SER A 181;THR A 135;ASP A 185","None","0.78A","1m4iA-4llaA:undetectable","1m4iA-4llaA:21.78"],["3V4T_E_ACTE503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","4lla","LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2","Homo sapiens",3,"GLN A  26;THR A  64;ASN A  62","None","0.85A","3v4tE-4llaA:undetectable","3v4tE-4llaA:19.54"],["4OKB_A_198A1002_2","ANDROGEN RECEPTOR","4lla","LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2","Homo sapiens",4,"LEU A 196;MET A 165;LEU A 138;VAL A  16","None","0.89A","4okbA-4llaA:undetectable","4okbA-4llaA:20.23"],["5KF8_A_GCSA404_1","PREDICTED ACETYLTRANSFERASE","4lla","LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 2","Homo sapiens",4,"ARG A  77;GLU A  41;GLY A  74;ASP A  96","None","1.08A","5kf8A-4llaA:undetectable","5kf8A-4llaA:18.52"]]