SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lle'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_B_ACTB1867_0 (FPRA)	4lle	PROBABLE TWO-COMPONENT SENSOR (Pseudomonas aeruginosa)	4 / 4	ALA A 96 ARG A 95 GLN A 93 GLU A 92	None	1.45A	1lqtB-4lleA: undetectable	1lqtB-4lleA: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1424_0 (FPRA)	4lle	PROBABLE TWO-COMPONENT SENSOR (Pseudomonas aeruginosa)	4 / 4	ALA A 96 ARG A 95 GLN A 93 GLU A 92	None	1.44A	1lquB-4lleA: undetectable	1lquB-4lleA: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NHZ_A_486A800_1 (GLUCOCORTICOID RECEPTOR)	4lle	PROBABLE TWO-COMPONENT SENSOR (Pseudomonas aeruginosa)	5 / 12	LEU A 60 GLY A 64 VAL A 68 GLN A 150 LEU A 146	None GOL A 201 (-3.7A) None None None	0.99A	1nhzA-4lleA: undetectable	1nhzA-4lleA: 18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECL_A_ILEA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4lle	PROBABLE TWO-COMPONENT SENSOR (Pseudomonas aeruginosa)	4 / 6	ALA A 51 THR A 52 VAL A 55 HIS A 48	None	1.04A	5eclA-4lleA: undetectable	5eclA-4lleA: 14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC3_B_486B801_1 (GLUCOCORTICOID RECEPTOR)	4lle	PROBABLE TWO-COMPONENT SENSOR (Pseudomonas aeruginosa)	5 / 12	LEU A 60 GLY A 64 VAL A 68 GLN A 150 LEU A 146	None GOL A 201 (-3.7A) None None None	0.91A	5uc3B-4lleA: undetectable	5uc3B-4lleA: 25.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_B_ACTB1867_0","FPRA","4lle","PROBABLE TWO-COMPONENT SENSOR","Pseudomonas aeruginosa",4,"ALA A  96;ARG A  95;GLN A  93;GLU A  92","None","1.45A","1lqtB-4lleA:undetectable","1lqtB-4lleA:14.68"],["1LQU_B_ACTB1424_0","FPRA","4lle","PROBABLE TWO-COMPONENT SENSOR","Pseudomonas aeruginosa",4,"ALA A  96;ARG A  95;GLN A  93;GLU A  92","None","1.44A","1lquB-4lleA:undetectable","1lquB-4lleA:14.68"],["1NHZ_A_486A800_1","GLUCOCORTICOID RECEPTOR","4lle","PROBABLE TWO-COMPONENT SENSOR","Pseudomonas aeruginosa",5,"LEU A  60;GLY A  64;VAL A  68;GLN A 150;LEU A 146","None;GOL A 201 (-3.7A);None;None;None","0.99A","1nhzA-4lleA:undetectable","1nhzA-4lleA:18.82"],["5ECL_A_ILEA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4lle","PROBABLE TWO-COMPONENT SENSOR","Pseudomonas aeruginosa",4,"ALA A  51;THR A  52;VAL A  55;HIS A  48","None","1.04A","5eclA-4lleA:undetectable","5eclA-4lleA:14.03"],["5UC3_B_486B801_1","GLUCOCORTICOID RECEPTOR","4lle","PROBABLE TWO-COMPONENT SENSOR","Pseudomonas aeruginosa",5,"LEU A  60;GLY A  64;VAL A  68;GLN A 150;LEU A 146","None;GOL A 201 (-3.7A);None;None;None","0.91A","5uc3B-4lleA:undetectable","5uc3B-4lleA:25.20"]]