SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4llf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 8 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.90A 1v54C-4llfA:
undetectable
1v54J-4llfA:
undetectable		 1v54C-4llfA:
21.36
1v54J-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 LEU A 159
GLY A 244
VAL A 102
THR A 202
ILE A 196
 None
 1.42A 1z95A-4llfA:
undetectable		 1z95A-4llfA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		3 / 3 TRP A 136
GLU A 100
TYR A 250
 None
 1.09A 2a3aA-4llfA:
undetectable		 2a3aA-4llfA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 8 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.88A 2dyrC-4llfA:
undetectable
2dyrJ-4llfA:
undetectable		 2dyrC-4llfA:
21.36
2dyrJ-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 7 ARG A 167
ALA A 185
PRO A 181
ALA A 186
 None
 1.01A 2ejfA-4llfA:
undetectable		 2ejfA-4llfA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 1.13A 3ablP-4llfA:
undetectable
3ablW-4llfA:
undetectable		 3ablP-4llfA:
21.36
3ablW-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 7 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.93A 3asnC-4llfA:
undetectable
3asnJ-4llfA:
undetectable		 3asnC-4llfA:
21.36
3asnJ-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 8 THR A 118
PRO A 120
GLY A 232
PHE A 124
 None
 1.08A 3tzfB-4llfA:
undetectable		 3tzfB-4llfA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		3 / 3 ASP A 175
LYS A 174
ASP A 173
 None
 0.62A 4a7tA-4llfA:
undetectable		 4a7tA-4llfA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 4 ASN A 115
GLY A 232
ASP A 222
ASP A 178
 None
 1.08A 4n49A-4llfA:
undetectable		 4n49A-4llfA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 LEU A 159
GLY A 244
VAL A 102
THR A 202
ILE A 196
 None
 1.33A 4oktA-4llfA:
undetectable		 4oktA-4llfA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		3 / 3 TYR A 171
GLY A 180
PRO A 181
 None
 0.64A 4qwpA-4llfA:
undetectable		 4qwpA-4llfA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLU A 100
TYR A 250
LEU A 152
PHE A 134
 None
 1.39A 4twdF-4llfA:
undetectable
4twdG-4llfA:
undetectable		 4twdF-4llfA:
23.20
4twdG-4llfA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		3 / 3 ASP A 123
ARG A 278
PRO A 282
 None
 0.93A 4wanC-4llfA:
undetectable		 4wanC-4llfA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 PHE A 255
LYS A 148
ASN A 127
PRO A 128
 None
 1.18A 4yv5B-4llfA:
undetectable		 4yv5B-4llfA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 PHE A 255
LYS A 148
ASN A 127
PRO A 128
 None
 1.18A 4yv5A-4llfA:
undetectable		 4yv5A-4llfA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 1.03A 5b1bC-4llfA:
undetectable
5b1bJ-4llfA:
undetectable		 5b1bC-4llfA:
21.36
5b1bJ-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCL_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 ARG A 114
GLY A 117
ASN A 116
TYR A 236
PHE A 112
 None
 1.43A 5cclA-4llfA:
undetectable		 5cclA-4llfA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 ILE A  96
ILE A 140
VAL A 252
ASN A 130
ILE A 215
 None
 1.19A 5lg3J-4llfA:
undetectable		 5lg3J-4llfA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 8 GLY A 119
ARG A 299
TRP A 233
ASP A 123
 None
 1.01A 5vlmB-4llfA:
undetectable		 5vlmB-4llfA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 TYR A 171
GLY A 232
ASN A 227
ASP A 222
ASP A 178
 None
 1.24A 5yn6A-4llfA:
undetectable		 5yn6A-4llfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 TYR A 171
GLY A 232
ASN A 227
ASP A 222
ASP A 178
 None
 1.24A 5yniA-4llfA:
undetectable		 5yniA-4llfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		5 / 12 TYR A 171
GLY A 232
ASN A 227
ASP A 222
ASP A 178
 None
 1.25A 5ynmA-4llfA:
undetectable		 5ynmA-4llfA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.91A 5z84P-4llfA:
undetectable
5z84W-4llfA:
undetectable		 5z84P-4llfA:
21.36
5z84W-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 1.00A 5z85P-4llfA:
undetectable
5z85W-4llfA:
undetectable		 5z85P-4llfA:
21.36
5z85W-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.84A 5z86C-4llfA:
undetectable
5z86J-4llfA:
undetectable		 5z86C-4llfA:
21.36
5z86J-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.88A 5z86P-4llfA:
undetectable
5z86W-4llfA:
undetectable		 5z86P-4llfA:
21.36
5z86W-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.88A 5zcoP-4llfA:
undetectable
5zcoW-4llfA:
undetectable		 5zcoP-4llfA:
21.36
5zcoW-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.84A 5zcpC-4llfA:
undetectable
5zcpJ-4llfA:
undetectable		 5zcpC-4llfA:
21.36
5zcpJ-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		4 / 6 GLN A 230
PHE A 154
LEU A 152
PHE A 149
 None
 0.93A 5zcpP-4llfA:
undetectable
5zcpW-4llfA:
undetectable		 5zcpP-4llfA:
21.36
5zcpW-4llfA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4llf CAPSID PROTEIN
(Cucumber
necrosis
virus) 		3 / 3 ASP A 293
SER A 322
SER A 320
 None
 0.84A 6mxtA-4llfA:
undetectable		 6mxtA-4llfA:
23.00