SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4llo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E71_M_ASCM995_0 (MYROSINASE MA1)	4llo	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (Mus musculus)	4 / 7	ILE B 97 PHE B 130 PHE B 49 PHE B 69	None	1.09A	1e71M-4lloB: undetectable	1e71M-4lloB: 15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E72_M_ASCM995_0 (MYROSINASE MA1)	4llo	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (Mus musculus)	4 / 7	ILE B 97 PHE B 130 PHE B 49 PHE B 69	None	1.09A	1e72M-4lloB: undetectable	1e72M-4lloB: 15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7R_A_NCTA440_1 (CYTOCHROME P450-CAM)	4llo	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (Mus musculus)	4 / 7	PHE B 87 VAL B 31 VAL B 111 ILE B 113	None	1.01A	1p7rA-4lloB: undetectable	1p7rA-4lloB: 14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4llo	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (Mus musculus)	5 / 12	THR B 79 PHE B 109 ASP B 132 ILE B 133 THR B 134	None	1.29A	3iv6A-4lloB: undetectable	3iv6A-4lloB: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KHP_A_PARA1606_1 (16S RIBOSOMAL RNA 30S RIBOSOMAL PROTEIN S9 30S RIBOSOMAL PROTEIN S10)	4llo	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (Mus musculus)	3 / 3	TYR B 44 ARG B 57 SER B 45	None	1.05A	4khpI-4lloB: undetectable 4khpJ-4lloB: undetectable	4khpI-4lloB: 22.07 4khpJ-4lloB: 23.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E71_M_ASCM995_0","MYROSINASE MA1","4llo","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1","Mus musculus",4,"ILE B  97;PHE B 130;PHE B  49;PHE B  69","None","1.09A","1e71M-4lloB:undetectable","1e71M-4lloB:15.07"],["1E72_M_ASCM995_0","MYROSINASE MA1","4llo","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1","Mus musculus",4,"ILE B  97;PHE B 130;PHE B  49;PHE B  69","None","1.09A","1e72M-4lloB:undetectable","1e72M-4lloB:15.07"],["1P7R_A_NCTA440_1","CYTOCHROME P450-CAM","4llo","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1","Mus musculus",4,"PHE B  87;VAL B  31;VAL B 111;ILE B 113","None","1.01A","1p7rA-4lloB:undetectable","1p7rA-4lloB:14.98"],["3IV6_A_SAMA301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4llo","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1","Mus musculus",5,"THR B  79;PHE B 109;ASP B 132;ILE B 133;THR B 134","None","1.29A","3iv6A-4lloB:undetectable","3iv6A-4lloB:19.85"],["4KHP_A_PARA1606_1","16S RIBOSOMAL RNA;30S RIBOSOMAL PROTEIN S9;30S RIBOSOMAL PROTEIN S10","4llo","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1","Mus musculus",3,"TYR B  44;ARG B  57;SER B  45","None","1.05A","4khpI-4lloB:undetectable;4khpJ-4lloB:undetectable","4khpI-4lloB:22.07;4khpJ-4lloB:23.94"]]