SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4llr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
CYH A  52
ARG A 128
 None
 0.48A 1h4oB-4llrA:
17.5		 1h4oB-4llrA:
27.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
CYH A  52
ARG A 128
 None
 0.49A 1h4oG-4llrA:
17.3		 1h4oG-4llrA:
27.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
CYH A  52
ARG A 128
 None
 0.49A 1oc3A-4llrA:
17.2		 1oc3A-4llrA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
 0.47A 2v32C-4llrA:
22.8
2v32D-4llrA:
22.9		 2v32C-4llrA:
29.31
2v32D-4llrA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
 0.45A 2v41C-4llrA:
23.1
2v41D-4llrA:
23.0		 2v41C-4llrA:
29.31
2v41D-4llrA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
 0.53A 2v41C-4llrA:
23.1
2v41D-4llrA:
23.0		 2v41C-4llrA:
29.31
2v41D-4llrA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PRO A  45
THR A  49
VAL A  51
ARG A 128
 None
 0.52A 2v41G-4llrA:
22.7
2v41H-4llrA:
22.7		 2v41G-4llrA:
29.31
2v41H-4llrA:
29.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 8 PHE A  43
VAL A 125
PRO A  45
ARG A 151
 None
 1.11A 3bgdB-4llrA:
undetectable		 3bgdB-4llrA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		5 / 10 LEU A   8
ALA A  12
ILE A 142
PHE A 163
CYH A  71
 None
 1.08A 3qpsA-4llrA:
undetectable		 3qpsA-4llrA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 7 LEU A  41
PHE A  43
MET A 113
LYS A 110
 None
 1.04A 4hbfA-4llrA:
undetectable		 4hbfA-4llrA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 7 LEU A  41
PHE A  43
MET A 113
LYS A 110
 None
 1.00A 4hc3A-4llrA:
undetectable		 4hc3A-4llrA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 7 PHE A 163
ASN A 138
ASP A 134
TRP A  38
 None
 1.44A 4kcnB-4llrA:
undetectable		 4kcnB-4llrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 6 ALA A  12
GLN A 137
LEU A 139
LEU A  39
 None
 0.82A 4xoyA-4llrA:
undetectable		 4xoyA-4llrA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		4 / 6 ALA A  12
GLN A 137
LEU A 139
LEU A  39
 None
 0.74A 4xp3A-4llrA:
undetectable		 4xp3A-4llrA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 4llr TRYPAREDOXIN
PEROXIDASE
(Trypanosoma
cruzi) 		5 / 10 ALA A 156
THR A  54
PHE A  59
PHE A  42
VAL A  40
 None
 1.35A 6hu9C-4llrA:
undetectable		 6hu9C-4llrA:
19.58