SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 ILE A 377
ALA A 537
THR A 337
ILE A 335
LEU A 374
 HEC  A 807 ( 4.4A)
None
None
None
None
 1.12A 1dhfB-4lm8A:
undetectable		 1dhfB-4lm8A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 7 SER A 484
GLY A 480
THR A 434
THR A 477
 None
 0.97A 1gtnF-4lm8A:
undetectable
1gtnG-4lm8A:
1.1		 1gtnF-4lm8A:
8.09
1gtnG-4lm8A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 9 GLY A 604
ALA A 593
THR A 596
SER A 607
ALA A 646
 None
 1.36A 1gtnQ-4lm8A:
undetectable
1gtnR-4lm8A:
undetectable		 1gtnQ-4lm8A:
8.09
1gtnR-4lm8A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 GLY A 514
MET A 517
CYH A 538
THR A 540
ILE A 377
 None
HEC  A 807 ( 3.8A)
HEC  A 807 (-1.7A)
HEC  A 807 (-4.7A)
HEC  A 807 ( 4.4A)
 1.41A 1m2zD-4lm8A:
undetectable		 1m2zD-4lm8A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 5 ILE A 180
LEU A  91
ALA A 103
GLU A  94
 HEC  A 803 (-3.8A)
None
None
None
 1.21A 1xvaA-4lm8A:
undetectable
1xvaB-4lm8A:
undetectable		 1xvaA-4lm8A:
17.37
1xvaB-4lm8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		3 / 3 THR A 611
PRO A 609
THR A 613
 HEC  A 810 (-3.9A)
None
HEC  A 808 (-4.6A)
 0.72A 209dC-4lm8A:
undetectable		 209dC-4lm8A:
2.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 6 HIS A 190
ASP A 567
TYR A 569
HIS A 233
 HEC  A 801 (-3.2A)
HEC  A 806 ( 4.6A)
EDO  A 821 (-4.5A)
HEC  A 801 ( 3.3A)
 1.43A 2dysA-4lm8A:
undetectable
2dysC-4lm8A:
undetectable		 2dysA-4lm8A:
21.79
2dysC-4lm8A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 7 HIS A 190
ASP A 567
TYR A 569
HIS A 233
 HEC  A 801 (-3.2A)
HEC  A 806 ( 4.6A)
EDO  A 821 (-4.5A)
HEC  A 801 ( 3.3A)
 1.43A 2eilA-4lm8A:
undetectable
2eilC-4lm8A:
undetectable		 2eilA-4lm8A:
21.79
2eilC-4lm8A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 7 THR A 419
ASP A 393
SER A 437
VAL A 439
 None
 1.03A 2hdnE-4lm8A:
undetectable
2hdnF-4lm8A:
undetectable
2hdnH-4lm8A:
undetectable		 2hdnE-4lm8A:
4.82
2hdnF-4lm8A:
19.21
2hdnH-4lm8A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 7 SER A 437
VAL A 439
THR A 419
ASP A 393
 None
 1.05A 2hdnF-4lm8A:
undetectable
2hdnG-4lm8A:
undetectable
2hdnH-4lm8A:
undetectable		 2hdnF-4lm8A:
19.21
2hdnG-4lm8A:
4.82
2hdnH-4lm8A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 6 THR A 419
ASP A 393
SER A 437
VAL A 439
 None
 1.09A 2hdnI-4lm8A:
undetectable
2hdnJ-4lm8A:
undetectable
2hdnL-4lm8A:
undetectable		 2hdnI-4lm8A:
4.82
2hdnJ-4lm8A:
19.21
2hdnL-4lm8A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 6 SER A 437
VAL A 439
THR A 419
ASP A 393
 None
 1.01A 2hdnJ-4lm8A:
undetectable
2hdnK-4lm8A:
undetectable
2hdnL-4lm8A:
undetectable		 2hdnJ-4lm8A:
19.21
2hdnK-4lm8A:
4.82
2hdnL-4lm8A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 5 PHE A 126
PHE A 129
PHE A 135
VAL A  65
 None
 1.10A 2lh6A-4lm8A:
undetectable		 2lh6A-4lm8A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 ILE A 377
ALA A 537
LEU A 521
THR A 337
ILE A 335
 HEC  A 807 ( 4.4A)
None
None
None
None
 1.08A 2w3bA-4lm8A:
undetectable		 2w3bA-4lm8A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 THR A 140
ASP A 166
VAL A 164
SER A 208
ASN A 179
 None
 1.11A 2y03B-4lm8A:
undetectable		 2y03B-4lm8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 5 TYR A  58
GLN A 141
ILE A  92
LEU A 139
 None
 1.27A 3ls4L-4lm8A:
2.6		 3ls4L-4lm8A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 GLY A 514
MET A 517
LEU A 521
THR A 540
ILE A 377
 None
HEC  A 807 ( 3.8A)
None
HEC  A 807 (-4.7A)
HEC  A 807 ( 4.4A)
 1.49A 3mneA-4lm8A:
undetectable		 3mneA-4lm8A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 11 ILE A 377
ALA A 537
THR A 337
ILE A 335
LEU A 374
 HEC  A 807 ( 4.4A)
None
None
None
None
 1.01A 3n0hA-4lm8A:
undetectable		 3n0hA-4lm8A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 ILE A 377
ALA A 537
THR A 337
ILE A 335
LEU A 374
 HEC  A 807 ( 4.4A)
None
None
None
None
 0.98A 3s3vA-4lm8A:
undetectable		 3s3vA-4lm8A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 10 ASN A 584
PHE A 583
THR A 613
ILE A 610
PHE A 656
 None
HEC  A 808 (-4.1A)
HEC  A 808 (-4.6A)
None
None
 1.33A 3t3qA-4lm8A:
undetectable		 3t3qA-4lm8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 7 LEU A 152
GLY A 120
ALA A  69
PHE A  68
 None
None
None
EDO  A 817 (-4.8A)
 0.91A 3tehB-4lm8A:
undetectable		 3tehB-4lm8A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		3 / 3 GLN A 141
PHE A 135
TYR A  58
 None
 1.00A 3ucjA-4lm8A:
undetectable		 3ucjA-4lm8A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 6 GLU A 503
ILE A 330
ASN A 331
GLU A 336
 EDO  A 823 (-3.6A)
EDO  A 823 ( 4.2A)
EDO  A 823 (-3.3A)
None
 0.95A 4ejwB-4lm8A:
undetectable		 4ejwB-4lm8A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 11 SER A 298
HIS A 297
ASN A 305
CYH A 306
ASP A 302
 HEC  A 805 ( 4.5A)
HEC  A 805 (-3.2A)
EDO  A 820 ( 3.1A)
HEC  A 805 (-1.7A)
None
 1.49A 4fevE-4lm8A:
undetectable		 4fevE-4lm8A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 11 ASN A 305
CYH A 306
ASP A 302
SER A 298
HIS A 297
 EDO  A 820 ( 3.1A)
HEC  A 805 (-1.7A)
None
HEC  A 805 ( 4.5A)
HEC  A 805 (-3.2A)
 1.47A 4gkhA-4lm8A:
0.3
4gkhB-4lm8A:
1.6		 4gkhA-4lm8A:
16.91
4gkhB-4lm8A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 11 ASN A 305
CYH A 306
ASP A 302
SER A 298
HIS A 297
 EDO  A 820 ( 3.1A)
HEC  A 805 (-1.7A)
None
HEC  A 805 ( 4.5A)
HEC  A 805 (-3.2A)
 1.49A 4gkiI-4lm8A:
0.2
4gkiJ-4lm8A:
0.0		 4gkiI-4lm8A:
16.91
4gkiJ-4lm8A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 ILE A 377
ALA A 537
LEU A 521
THR A 337
ILE A 335
 HEC  A 807 ( 4.4A)
None
None
None
None
 1.08A 4kebB-4lm8A:
undetectable		 4kebB-4lm8A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 12 ILE A 377
ALA A 537
LEU A 521
THR A 337
ILE A 335
 HEC  A 807 ( 4.4A)
None
None
None
None
 1.08A 4m6kA-4lm8A:
undetectable		 4m6kA-4lm8A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 8 ALA A 385
PRO A 544
VAL A 539
PHE A 436
GLY A 381
 None
 1.06A 4zjzA-4lm8A:
undetectable		 4zjzA-4lm8A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 5 ILE A 335
LYS A 365
ILE A 367
VAL A 371
 None
 0.87A 5jmnA-4lm8A:
undetectable		 5jmnA-4lm8A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 8 ILE A 610
THR A 611
THR A 616
ARG A 553
 None
HEC  A 810 (-3.9A)
None
None
 1.13A 6c06C-4lm8A:
undetectable		 6c06C-4lm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		5 / 9 LEU A 521
THR A 518
GLY A 334
ILE A 335
PHE A 438
 None
EDO  A 823 ( 4.7A)
None
None
HEC  A 807 (-4.6A)
 1.33A 6ebpA-4lm8A:
undetectable		 6ebpA-4lm8A:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 4lm8 EXTRACELLULAR IRON
OXIDE RESPIRATORY
SYSTEM SURFACE
DECAHEME CYTOCHROME
C COMPONENT MTRC
(Shewanella
oneidensis) 		4 / 8 VAL A 223
TRP A 239
HIS A 230
CYH A 282
 None
HEC  A 801 ( 4.8A)
HEC  A 803 (-3.2A)
HEC  A 804 (-1.8A)
 1.32A 6gneB-4lm8A:
undetectable		 6gneB-4lm8A:
21.66