SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 4lms CRYPTOPHYTE
PHYCOCYANIN (BETA
CHAIN)
(Chroomonas
sp.) 		4 / 9 ILE B  89
ALA B 128
VAL B 131
LYS B 135
 None
 0.98A 2vufB-4lmsB:
3.1		 2vufB-4lmsB:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 4lms CRYPTOPHYTE
PHYCOCYANIN (ALPHA-1
CHAIN)
(Chroomonas
sp.) 		3 / 3 VAL A  48
SER A  49
THR A  52
 None
 0.38A 4luhA-4lmsA:
undetectable		 4luhA-4lmsA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4lms CRYPTOPHYTE
PHYCOCYANIN (BETA
CHAIN)
(Chroomonas
sp.) 		4 / 5 GLY B 100
TYR B  92
GLU B 164
ASP B 101
 None
 1.31A 4xueA-4lmsB:
undetectable		 4xueA-4lmsB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 4lms CRYPTOPHYTE
PHYCOCYANIN (BETA
CHAIN)
(Chroomonas
sp.) 		5 / 12 ASN B  63
CYH B  73
ARG B  78
CYH B  82
LEU B  66
 None
CYC  B 203 (-3.6A)
None
CYC  B 203 (-1.8A)
CYC  B 203 ( 4.8A)
 1.34A 5lsuA-4lmsB:
undetectable		 5lsuA-4lmsB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 4lms CRYPTOPHYTE
PHYCOCYANIN (BETA
CHAIN)
(Chroomonas
sp.) 		5 / 12 GLY B 121
ASN B  63
CYH B  73
CYH B  82
LEU B  66
 MEN  B  72 ( 4.6A)
None
CYC  B 203 (-3.6A)
CYC  B 203 (-1.8A)
CYC  B 203 ( 4.8A)
 1.34A 5lsuA-4lmsB:
undetectable		 5lsuA-4lmsB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 4lms CRYPTOPHYTE
PHYCOCYANIN (ALPHA-1
CHAIN)
CRYPTOPHYTE
PHYCOCYANIN (BETA
CHAIN)
(Chroomonas
sp.) 		3 / 3 VAL B  19
LYS B  15
MET A  43
 None
None
P6G  B 204 (-3.6A)
 0.72A 5nknA-4lmsB:
undetectable		 5nknA-4lmsB:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4lms CRYPTOPHYTE
PHYCOCYANIN (ALPHA-1
CHAIN)
CRYPTOPHYTE
PHYCOCYANIN (BETA
CHAIN)
(Chroomonas
sp.) 		4 / 5 TYR A  25
TYR B  18
GLY B  20
GLY B  21
 M1V  A 101 (-4.7A)
M1V  A 101 (-4.7A)
M1V  A 101 ( 3.7A)
M1V  A 101 ( 4.8A)
 1.16A 5x7pA-4lmsA:
undetectable		 5x7pA-4lmsA:
4.80