SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ln2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 4ln2 SORBIN AND SH3
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 916
PHE A 878
SER A 887
VAL A 923
ARG A 898
 None
 1.33A 3dlcA-4ln2A:
undetectable		 3dlcA-4ln2A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4ln2 SORBIN AND SH3
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ILE A 917
VAL A 900
ARG A 898
 None
 0.75A 3p73A-4ln2A:
undetectable		 3p73A-4ln2A:
12.00