SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 11 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.27A 1pk9C-4lnqA:
undetectable		 1pk9C-4lnqA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 9 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.33A 1pw7B-4lnqA:
undetectable		 1pw7B-4lnqA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 9 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.32A 1pw7C-4lnqA:
undetectable		 1pw7C-4lnqA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 8 LEU A 156
ILE A 197
ILE A 161
THR A 168
 None
 0.84A 1sbrA-4lnqA:
undetectable		 1sbrA-4lnqA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 7 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.07A 1v55C-4lnqA:
undetectable
1v55J-4lnqA:
undetectable		 1v55C-4lnqA:
19.62
1v55J-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 11 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.26A 1vhwA-4lnqA:
undetectable
1vhwD-4lnqA:
undetectable		 1vhwA-4lnqA:
21.67
1vhwD-4lnqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 11 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.31A 1vhwC-4lnqA:
undetectable
1vhwE-4lnqA:
undetectable		 1vhwC-4lnqA:
21.67
1vhwE-4lnqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 11 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.30A 1vhwA-4lnqA:
undetectable
1vhwD-4lnqA:
undetectable		 1vhwA-4lnqA:
21.67
1vhwD-4lnqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 11 MET A  62
SER A  91
VAL A 144
GLU A  90
ILE A 149
 None
 1.28A 1vhwC-4lnqA:
undetectable
1vhwE-4lnqA:
undetectable		 1vhwC-4lnqA:
21.67
1vhwE-4lnqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 7 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.07A 2eijC-4lnqA:
undetectable
2eijJ-4lnqA:
undetectable		 2eijC-4lnqA:
19.62
2eijJ-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 7 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.03A 2eimC-4lnqA:
undetectable
2eimJ-4lnqA:
undetectable		 2eimC-4lnqA:
19.62
2eimJ-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 6 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.09A 3wg7C-4lnqA:
undetectable
3wg7J-4lnqA:
undetectable		 3wg7C-4lnqA:
19.62
3wg7J-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		3 / 3 GLY A 235
SER A 234
TRP A 201
 None
 0.83A 4e7cD-4lnqA:
undetectable		 4e7cD-4lnqA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		5 / 12 GLU A 126
ILE A 115
VAL A  96
VAL A  87
VAL A  64
 None
 1.08A 5dpdA-4lnqA:
undetectable		 5dpdA-4lnqA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 5 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.16A 5iy5P-4lnqA:
undetectable
5iy5W-4lnqA:
undetectable		 5iy5P-4lnqA:
20.08
5iy5W-4lnqA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 6 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.09A 5w97C-4lnqA:
undetectable
5w97J-4lnqA:
undetectable		 5w97C-4lnqA:
19.62
5w97J-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 7 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.02A 5x1fP-4lnqA:
undetectable
5x1fW-4lnqA:
undetectable		 5x1fP-4lnqA:
19.62
5x1fW-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 5 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.06A 5xdxC-4lnqA:
undetectable
5xdxJ-4lnqA:
undetectable		 5xdxC-4lnqA:
20.00
5xdxJ-4lnqA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4lnq INTERFERON-ACTIVABLE
PROTEIN 202
(Mus
musculus) 		4 / 5 LEU A 218
PHE A 239
LEU A 216
PHE A 188
 None
 1.12A 5xdxP-4lnqA:
undetectable
5xdxW-4lnqA:
undetectable		 5xdxP-4lnqA:
20.00
5xdxW-4lnqA:
14.29