SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		4 / 5 THR A 294
THR A 317
GLU A  -6
THR A  -7
 None
 1.39A 1d4fB-4lobA:
undetectable		 1d4fB-4lobA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		4 / 8 TYR A 167
ASP A 215
ASP A 233
LEU A 152
 None
 1.04A 1pk2A-4lobA:
undetectable		 1pk2A-4lobA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.95A 1rqjA-4lobA:
28.5		 1rqjA-4lobA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.95A 1rqjA-4lobA:
28.5		 1rqjA-4lobA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.91A 1rqjB-4lobA:
28.4		 1rqjB-4lobA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.92A 1rqjB-4lobA:
28.4		 1rqjB-4lobA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		4 / 6 GLY A 204
HIS A 205
ASN A 208
PHE A 210
 GOL  A 401 ( 3.8A)
GOL  A 401 (-3.4A)
GOL  A 401 (-3.8A)
None
 0.83A 1xf1B-4lobA:
undetectable		 1xf1B-4lobA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A 189
ALA A 187
ILE A 188
ALA A 203
LEU A 178
 None
 1.20A 1xp0A-4lobA:
2.2		 1xp0A-4lobA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.88A 1yhlA-4lobA:
26.4		 1yhlA-4lobA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.87A 1yhlA-4lobA:
26.4		 1yhlA-4lobA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.91A 1yq7A-4lobA:
26.8		 1yq7A-4lobA:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.89A 1yq7A-4lobA:
26.8		 1yq7A-4lobA:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.83A 1yv5A-4lobA:
27.1		 1yv5A-4lobA:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.85A 1yv5A-4lobA:
27.1		 1yv5A-4lobA:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.84A 2f8cF-4lobA:
27.8		 2f8cF-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.87A 2f8cF-4lobA:
27.8		 2f8cF-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.82A 2f8zF-4lobA:
28.1		 2f8zF-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.85A 2f8zF-4lobA:
28.1		 2f8zF-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.84A 2f94F-4lobA:
27.5		 2f94F-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.86A 2f94F-4lobA:
27.5		 2f94F-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.89A 2f9kF-4lobA:
27.6		 2f9kF-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.88A 2f9kF-4lobA:
27.6		 2f9kF-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		3 / 3 LEU A 127
LEU A  23
MET A  20
 None
 0.73A 2itzA-4lobA:
undetectable		 2itzA-4lobA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
LYS A 238
 None
 0.61A 2o1oB-4lobA:
25.6		 2o1oB-4lobA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.88A 3ez3D-4lobA:
26.6		 3ez3D-4lobA:
28.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.79A 3ez3D-4lobA:
26.6		 3ez3D-4lobA:
28.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.88A 3n45F-4lobA:
27.9		 3n45F-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.86A 3n45F-4lobA:
27.9		 3n45F-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.88A 3n46F-4lobA:
27.6		 3n46F-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.87A 3n46F-4lobA:
27.6		 3n46F-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 ILE A 258
ALA A 246
ILE A 171
TYR A 167
THR A 175
 None
 1.25A 3prsA-4lobA:
undetectable		 3prsA-4lobA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 9 ASP A 129
GLY A  27
ILE A  28
ILE A  77
ILE A  76
 None
 0.92A 3s56B-4lobA:
undetectable		 3s56B-4lobA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		3 / 3 TYR A 309
LEU A 201
ARG A 310
 None
GOL  A 401 (-4.2A)
None
 0.71A 3sufB-4lobA:
undetectable		 3sufB-4lobA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		3 / 3 LYS A 238
THR A 240
ILE A 216
 None
 0.85A 4e0fB-4lobA:
undetectable		 4e0fB-4lobA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		3 / 3 GLU A 180
ARG A 177
HIS A 172
 GOL  A 401 (-2.7A)
None
GOL  A 401 (-3.7A)
 0.69A 4kf9A-4lobA:
undetectable		 4kf9A-4lobA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.84A 4kpdA-4lobA:
27.7		 4kpdA-4lobA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.87A 4kpdA-4lobA:
27.7		 4kpdA-4lobA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 9 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.90A 4kpjA-4lobA:
26.9		 4kpjA-4lobA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.90A 4kq5A-4lobA:
27.1		 4kq5A-4lobA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.87A 4kqsA-4lobA:
27.5		 4kqsA-4lobA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.88A 4kqsA-4lobA:
27.5		 4kqsA-4lobA:
29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.85A 4nkeA-4lobA:
27.0		 4nkeA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.85A 4nkeA-4lobA:
27.0		 4nkeA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 9 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.92A 4nkfA-4lobA:
27.4		 4nkfA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 9 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.89A 4nkfA-4lobA:
27.4		 4nkfA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.86A 4nuaA-4lobA:
27.4		 4nuaA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.86A 4nuaA-4lobA:
27.4		 4nuaA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 9 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.85A 4oguA-4lobA:
27.2		 4oguA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 9 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.84A 4oguA-4lobA:
27.2		 4oguA-4lobA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.85A 4p0wA-4lobA:
27.8		 4p0wA-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.90A 4p0wA-4lobA:
27.8		 4p0wA-4lobA:
28.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.87A 4rxdA-4lobA:
25.7		 4rxdA-4lobA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.84A 4rxdA-4lobA:
25.7		 4rxdA-4lobA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.85A 4rxdB-4lobA:
26.1		 4rxdB-4lobA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.84A 4rxdB-4lobA:
26.1		 4rxdB-4lobA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.86A 4rxdC-4lobA:
26.1		 4rxdC-4lobA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 10 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.84A 4rxdC-4lobA:
26.1		 4rxdC-4lobA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		3 / 3 SER A 280
GLU A 164
GLU A 293
 None
 0.78A 4ymgB-4lobA:
undetectable		 4ymgB-4lobA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.87A 5cg5A-4lobA:
27.0		 5cg5A-4lobA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.86A 5cg5A-4lobA:
27.0		 5cg5A-4lobA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  85
ASP A  88
LYS A 174
THR A 175
GLN A 211
 None
 0.87A 5cg6A-4lobA:
27.5		 5cg6A-4lobA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  85
LYS A 174
THR A 175
GLN A 211
ASP A 214
 None
 0.88A 5cg6A-4lobA:
27.5		 5cg6A-4lobA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4lob POLYPRENYL
SYNTHETASE
(Acinetobacter
baumannii) 		5 / 11 LEU A  73
GLU A 180
LEU A 189
THR A 183
ALA A 186
 None
GOL  A 401 (-2.7A)
None
None
None
 1.12A 5o96A-4lobA:
undetectable
5o96B-4lobA:
undetectable		 5o96A-4lobA:
22.55
5o96B-4lobA:
22.55