SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		3 / 3 ALA A  76
VAL A  78
TRP A  51
 None
 0.92A 1bdwA-4lp4A:
undetectable
1bdwB-4lp4A:
undetectable		 1bdwA-4lp4A:
4.25
1bdwB-4lp4A:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_A_NCAA303_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		5 / 9 HIS A 158
LEU A 155
SER A 209
SER A 190
GLU A 175
 None
 1.38A 1ismA-4lp4A:
0.0		 1ismA-4lp4A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		4 / 7 VAL A 173
SER A 190
LEU A 164
HIS A 158
 None
 1.15A 2f78B-4lp4A:
undetectable		 2f78B-4lp4A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		4 / 6 VAL A 173
SER A 190
LEU A 164
HIS A 158
 None
 1.13A 2f8dA-4lp4A:
undetectable		 2f8dA-4lp4A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		3 / 3 ARG A 228
THR A 134
TRP A 230
 None
 1.00A 4d7hA-4lp4A:
undetectable		 4d7hA-4lp4A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		4 / 7 GLY A  82
VAL A  78
PRO A  80
ASN A  81
 None
 0.83A 4forA-4lp4A:
undetectable		 4forA-4lp4A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		3 / 3 ARG A 228
THR A 134
TRP A 230
 None
 1.03A 4ug5A-4lp4A:
undetectable		 4ug5A-4lp4A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		3 / 3 ARG A 228
THR A 134
TRP A 230
 None
 0.96A 4uglA-4lp4A:
undetectable		 4uglA-4lp4A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR
(Homo
sapiens) 		3 / 3 ARG A 228
THR A 134
TRP A 230
 None
 1.02A 5g6cA-4lp4A:
undetectable		 5g6cA-4lp4A:
19.00