SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		5 / 12 ILE A 223
ILE A 203
MET A 120
ALA A  16
GLU A 225
 None
 1.42A 1ki7B-4lp7A:
undetectable		 1ki7B-4lp7A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		4 / 5 PRO A  13
ILE A  12
GLY A  11
TYR A   9
 None
 1.07A 2jkjD-4lp7A:
undetectable		 2jkjD-4lp7A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		4 / 5 PRO A  13
ILE A  12
GLY A  11
TYR A   9
 None
 1.07A 2jkjF-4lp7A:
undetectable		 2jkjF-4lp7A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		5 / 12 LEU A  49
LEU A 117
VAL A  20
THR A  54
MET A  81
 None
 1.50A 2yloA-4lp7A:
undetectable		 2yloA-4lp7A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		4 / 7 PHE A  39
ALA A  76
THR A  54
LEU A  48
 None
 0.84A 4ejgA-4lp7A:
undetectable		 4ejgA-4lp7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		4 / 4 PHE A  88
LEU A  48
LEU A  55
VAL A  83
 None
 1.32A 5xxiA-4lp7A:
undetectable		 5xxiA-4lp7A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 4lp7 MATRIX PROTEIN M
(Human
metapneumovirus) 		5 / 12 ILE A 203
VAL A   6
ALA A 195
PHE A  36
LEU A  84
 None
 1.50A 6a7pB-4lp7A:
undetectable		 6a7pB-4lp7A:
17.41