SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4lq4 50S RIBOSOMAL
PROTEIN L1
(Methanocaldococc
us
jannaschii) 		5 / 10 VAL A 164
VAL A 181
ALA A 199
ALA A  30
ILE A 196
 None
 1.05A 1likA-4lq4A:
undetectable		 1likA-4lq4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 4lq4 50S RIBOSOMAL
PROTEIN L1
(Methanocaldococc
us
jannaschii) 		4 / 7 PRO A 130
GLU A  47
LEU A 146
LEU A 142
 None
 0.87A 4iomA-4lq4A:
undetectable		 4iomA-4lq4A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 4lq4 50S RIBOSOMAL
PROTEIN L1
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  63
ILE A 115
GLY A 120
ILE A 122
ILE A  80
 None
 1.01A 4q1yB-4lq4A:
undetectable		 4q1yB-4lq4A:
19.43