SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 4lqk PROTEIN A46
(Vaccinia
virus) 		4 / 6 LEU C 184
ARG C 159
TYR C  98
VAL C 150
 None
 1.10A 1db1A-4lqkC:
undetectable		 1db1A-4lqkC:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4lqk PROTEIN A46
(Vaccinia
virus) 		5 / 11 LEU C 116
LEU C 119
ALA C 120
ILE C  99
LEU C 167
 None
 1.14A 1g50A-4lqkC:
undetectable		 1g50A-4lqkC:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4lqk PROTEIN A46
(Vaccinia
virus) 		4 / 5 LEU C  95
ALA C 185
ILE C 188
SER C 165
 None
 1.08A 2othA-4lqkC:
undetectable		 2othA-4lqkC:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4lqk PROTEIN A46
(Vaccinia
virus) 		5 / 10 ILE C 160
PHE C  91
SER C  90
ALA C  96
LEU C  95
 None
 1.23A 3lw5B-4lqkC:
undetectable		 3lw5B-4lqkC:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 4lqk PROTEIN A46
(Vaccinia
virus) 		5 / 9 LEU C 116
SER C 195
LEU C 197
GLU C 196
ILE C 192
 None
 1.32A 6fdyU-4lqkC:
undetectable		 6fdyU-4lqkC:
22.94