SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA502_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4lql	L-ARABINOSE ISOMERASE (Lactobacillus fermentum)	3 / 3	GLU A 331 HIS A 348 HIS A 447	None	0.60A	1oe2A-4lqlA: undetectable	1oe2A-4lqlA: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_C_QPSC1060_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	4lql	L-ARABINOSE ISOMERASE (Lactobacillus fermentum)	5 / 12	VAL A 218 THR A 276 VAL A 293 GLY A 290 ALA A 292	None	1.28A	2x2iC-4lqlA: undetectable	2x2iC-4lqlA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKA_A_SAMA400_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H)	4lql	L-ARABINOSE ISOMERASE (Lactobacillus fermentum)	5 / 12	GLY A 307 ARG A 180 GLY A 304 ARG A 186 ASP A 183	None	1.19A	3tkaA-4lqlA: undetectable	3tkaA-4lqlA: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_C_GLYC713_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	4lql	L-ARABINOSE ISOMERASE (Lactobacillus fermentum)	3 / 3	GLN A 125 TYR A 19 ASN A 122	None	0.88A	6dwdC-4lqlA: undetectable	6dwdC-4lqlA: 21.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE2_A_CUA502_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4lql","L-ARABINOSE ISOMERASE","Lactobacillus fermentum",3,"GLU A 331;HIS A 348;HIS A 447","None","0.60A","1oe2A-4lqlA:undetectable","1oe2A-4lqlA:20.58"],["2X2I_C_QPSC1060_1","ALPHA-1,4-GLUCAN LYASE ISOZYME 1","4lql","L-ARABINOSE ISOMERASE","Lactobacillus fermentum",5,"VAL A 218;THR A 276;VAL A 293;GLY A 290;ALA A 292","None","1.28A","2x2iC-4lqlA:undetectable","2x2iC-4lqlA:17.39"],["3TKA_A_SAMA400_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H","4lql","L-ARABINOSE ISOMERASE","Lactobacillus fermentum",5,"GLY A 307;ARG A 180;GLY A 304;ARG A 186;ASP A 183","None","1.19A","3tkaA-4lqlA:undetectable","3tkaA-4lqlA:21.28"],["6DWD_C_GLYC713_0","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","4lql","L-ARABINOSE ISOMERASE","Lactobacillus fermentum",3,"GLN A 125;TYR A  19;ASN A 122","None","0.88A","6dwdC-4lqlA:undetectable","6dwdC-4lqlA:21.38"]]