SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.18A 1dz4B-4lqzA:
undetectable		 1dz4B-4lqzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.20A 1dz6A-4lqzA:
undetectable		 1dz6A-4lqzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.20A 1dz6B-4lqzA:
undetectable		 1dz6B-4lqzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.14A 1o76B-4lqzA:
undetectable		 1o76B-4lqzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.17A 1uyuB-4lqzA:
undetectable		 1uyuB-4lqzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A  72
ILE A 133
PHE A  68
ALA A 140
LEU A  98
 None
PO4  A 201 (-4.0A)
None
None
None
 1.11A 2qb4A-4lqzA:
undetectable		 2qb4A-4lqzA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A 110
ILE A  80
PHE A  94
LEU A 154
 None
 0.83A 2w98B-4lqzA:
undetectable		 2w98B-4lqzA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.19A 2zawA-4lqzA:
undetectable		 2zawA-4lqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 PHE A  79
THR A 141
VAL A  72
ASP A  70
 None
 1.01A 2zaxA-4lqzA:
undetectable		 2zaxA-4lqzA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 10 ILE A  80
ILE A  83
VAL A  87
GLY A  59
LEU A 154
 None
 1.10A 3em0A-4lqzA:
4.7		 3em0A-4lqzA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 TYR A  49
TYR A  67
GLY A   0
 None
 0.71A 3eteB-4lqzA:
undetectable
3eteD-4lqzA:
undetectable
3eteF-4lqzA:
undetectable		 3eteB-4lqzA:
16.98
3eteD-4lqzA:
16.98
3eteF-4lqzA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 PHE A  79
THR A 141
VAL A  72
ASP A  70
 None
 1.03A 3fwgB-4lqzA:
undetectable		 3fwgB-4lqzA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 HIS A  56
ILE A  57
TRP A  95
ILE A  80
 None
 0.70A 3sfeB-4lqzA:
undetectable
3sfeC-4lqzA:
undetectable		 3sfeB-4lqzA:
21.96
3sfeC-4lqzA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 ALA A  65
ILE A  83
ILE A  38
LEU A 154
ILE A  48
 None
 1.05A 4dt8A-4lqzA:
undetectable		 4dt8A-4lqzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 10 ALA A  65
ILE A  83
ILE A  38
LEU A 154
ILE A  48
 None
 1.11A 4dt8B-4lqzA:
undetectable		 4dt8B-4lqzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 10 ALA A  65
ILE A  83
ILE A  38
LEU A 154
ILE A  48
 None
 1.12A 4dtaA-4lqzA:
undetectable		 4dtaA-4lqzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.14A 4g3rA-4lqzA:
undetectable		 4g3rA-4lqzA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.14A 4g3rB-4lqzA:
undetectable		 4g3rB-4lqzA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.16A 4l4dA-4lqzA:
undetectable		 4l4dA-4lqzA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.17A 4l4eA-4lqzA:
undetectable		 4l4eA-4lqzA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4lqz UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  79
TYR A 100
VAL A  72
ASP A  70
 None
 1.16A 4l4fA-4lqzA:
undetectable		 4l4fA-4lqzA:
15.11