SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lrq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HMY_A_SAMA328_0 (HAEIII METHYLTRANSFERASE)	4lrq	PHOSPHOTYROSINE PROTEIN PHOSPHATASE (Vibrio cholerae)	4 / 8	PHE A 77 ILE A 72 THR A 40 LEU A 94	None	0.93A	1hmyA-4lrqA: 3.7	1hmyA-4lrqA: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_A_BEZA1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	4lrq	PHOSPHOTYROSINE PROTEIN PHOSPHATASE (Vibrio cholerae)	4 / 6	GLY A 39 THR A 40 SER A 15 VAL A 7	None	0.94A	5ewuA-4lrqA: undetectable	5ewuA-4lrqA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_B_BEZB1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	4lrq	PHOSPHOTYROSINE PROTEIN PHOSPHATASE (Vibrio cholerae)	4 / 6	GLY A 39 THR A 40 SER A 15 VAL A 7	None	0.99A	5ewuB-4lrqA: undetectable	5ewuB-4lrqA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_B_LLLB301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	4lrq	PHOSPHOTYROSINE PROTEIN PHOSPHATASE (Vibrio cholerae)	4 / 7	ARG A 60 TYR A 62 GLU A 139 ASP A 136	None	1.28A	6mn5B-4lrqA: undetectable	6mn5B-4lrqA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HMY_A_SAMA328_0","HAEIII METHYLTRANSFERASE","4lrq","PHOSPHOTYROSINE PROTEIN PHOSPHATASE","Vibrio cholerae",4,"PHE A  77;ILE A  72;THR A  40;LEU A  94","None","0.93A","1hmyA-4lrqA:3.7","1hmyA-4lrqA:21.66"],["5EWU_A_BEZA1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","4lrq","PHOSPHOTYROSINE PROTEIN PHOSPHATASE","Vibrio cholerae",4,"GLY A  39;THR A  40;SER A  15;VAL A   7","None","0.94A","5ewuA-4lrqA:undetectable","5ewuA-4lrqA:17.68"],["5EWU_B_BEZB1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","4lrq","PHOSPHOTYROSINE PROTEIN PHOSPHATASE","Vibrio cholerae",4,"GLY A  39;THR A  40;SER A  15;VAL A   7","None","0.99A","5ewuB-4lrqA:undetectable","5ewuB-4lrqA:17.68"],["6MN5_B_LLLB301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","4lrq","PHOSPHOTYROSINE PROTEIN PHOSPHATASE","Vibrio cholerae",4,"ARG A  60;TYR A  62;GLU A 139;ASP A 136","None","1.28A","6mn5B-4lrqA:undetectable","6mn5B-4lrqA:20.00"]]