SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8
(Bartonella
quintana) 		4 / 7 ILE A 101
ILE A 165
LEU A 219
LEU A 200
 None
 0.83A 3adxA-4lsoA:
undetectable		 3adxA-4lsoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8
(Bartonella
quintana) 		4 / 4 LEU A 131
ILE A 165
TYR A 226
TYR A 104
 None
 1.11A 3vt7A-4lsoA:
undetectable		 3vt7A-4lsoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8
(Bartonella
quintana) 		3 / 3 TYR A 104
ARG A 111
LYS A 108
 None
 1.38A 4wq5B-4lsoA:
undetectable		 4wq5B-4lsoA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8
(Bartonella
quintana) 		3 / 3 GLU A 225
TYR A 226
ARG A 113
 None
 0.85A 5uunA-4lsoA:
undetectable		 5uunA-4lsoA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8
(Bartonella
quintana) 		3 / 3 GLU A 225
TYR A 226
ARG A 113
 None
 0.68A 5uunB-4lsoA:
undetectable		 5uunB-4lsoA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4lso TYPE IV SECRETION
SYSTEM PROTEIN VIRB8
(Bartonella
quintana) 		4 / 7 ILE A 199
GLN A 177
VAL A 178
THR A 102
 None
 1.00A 6cduF-4lsoA:
undetectable
6cduG-4lsoA:
undetectable		 6cduF-4lsoA:
19.69
6cduG-4lsoA:
19.69