SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ltm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		4 / 8 HIS A 170
SER A 174
ARG A 134
ALA A 104
 None
 1.32A 2rk8A-4ltmA:
undetectable		 2rk8A-4ltmA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		5 / 12 VAL A  29
ARG A 172
VAL A 137
LEU A 106
LEU A 175
 None
 1.09A 4o1zB-4ltmA:
undetectable		 4o1zB-4ltmA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		3 / 3 LEU A 118
ASP A 121
TYR A 122
 None
 0.42A 4qc6B-4ltmA:
undetectable		 4qc6B-4ltmA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		6 / 12 LEU A 108
LEU A 106
ILE A  74
ILE A   5
VAL A  29
LEU A 164
 None
 1.18A 4y0sA-4ltmA:
undetectable		 4y0sA-4ltmA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		5 / 12 LEU A  55
LEU A  60
ILE A  43
ALA A  90
LEU A  87
 None
 1.19A 5ienB-4ltmA:
undetectable		 5ienB-4ltmA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		5 / 12 THR A  85
SER A  11
GLY A  10
ALA A  76
THR A  18
 None
FMN  A 201 (-2.4A)
None
None
FMN  A 201 (-3.6A)
 1.39A 5lf3b-4ltmA:
undetectable		 5lf3b-4ltmA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4ltm NADH-DEPENDENT FMN
REDUCTASE
(EDTA-degrading
bacterium
BNC1) 		5 / 12 THR A  85
SER A  11
GLY A  10
ALA A  76
THR A  18
 None
FMN  A 201 (-2.4A)
None
None
FMN  A 201 (-3.6A)
 1.39A 5lf3N-4ltmA:
undetectable		 5lf3N-4ltmA:
24.89