SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		4 / 5 LEU A 180
SER A  55
LEU A  56
GLY A  67
 None
 1.14A 1a4lB-4lu1A:
undetectable		 1a4lB-4lu1A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		3 / 3 ASN A  98
PHE A 151
VAL A 100
 None
 0.75A 1kijA-4lu1A:
undetectable		 1kijA-4lu1A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 10 LEU A   6
ARG A  14
PHE A  24
LEU A 177
ALA A  15
 None
 1.01A 2bxeB-4lu1A:
2.0		 2bxeB-4lu1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 11 ILE A  66
GLY A 105
THR A 104
LEU A 177
GLY A  67
 None
 1.16A 2fn1A-4lu1A:
undetectable		 2fn1A-4lu1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		4 / 6 LEU A 180
LEU A 177
ILE A  66
ARG A  13
 None
 0.97A 2rlfC-4lu1A:
undetectable
2rlfD-4lu1A:
undetectable		 2rlfC-4lu1A:
18.18
2rlfD-4lu1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 12 LEU A 108
ALA A  53
GLY A 114
HIS A 115
LEU A 116
 None
 0.80A 3olsA-4lu1A:
undetectable		 3olsA-4lu1A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 12 LEU A 108
ALA A  53
GLY A 114
HIS A 115
LEU A 116
 None
 1.03A 3q95A-4lu1A:
undetectable		 3q95A-4lu1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 12 LEU A 108
ALA A  53
GLY A 114
HIS A 115
LEU A 116
 None
 0.97A 3q95B-4lu1A:
undetectable		 3q95B-4lu1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 11 LEU A 108
ALA A  53
GLY A 114
HIS A 115
LEU A 116
 None
 1.01A 3uudA-4lu1A:
undetectable		 3uudA-4lu1A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		4 / 5 ASN A  87
LEU A  90
SER A 150
LEU A  74
 None
 1.31A 4n09C-4lu1A:
undetectable		 4n09C-4lu1A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 12 LEU A 108
ALA A  53
GLY A 114
HIS A 115
LEU A 116
 None
 0.92A 4pxmA-4lu1A:
undetectable		 4pxmA-4lu1A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 9 ARG A 185
LEU A 184
LEU A  17
ILE A  66
ALA A 179
 None
 1.31A 4z69A-4lu1A:
undetectable		 4z69A-4lu1A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 10 LEU A 108
ALA A  53
GLY A 114
HIS A 115
LEU A 116
 None
 0.91A 5dxbA-4lu1A:
undetectable		 5dxbA-4lu1A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 12 ALA A  57
PHE A 109
GLY A  67
SER A  68
GLU A  51
 None
 1.16A 5hfjD-4lu1A:
undetectable		 5hfjD-4lu1A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		4 / 4 ASN A  87
LEU A  90
SER A 150
LEU A  74
 None
 1.30A 5kb5A-4lu1A:
undetectable		 5kb5A-4lu1A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 4lu1 MAF-LIKE PROTEIN
YCEF
(Escherichia
coli) 		5 / 12 ALA A  49
GLY A  67
ASN A 170
LEU A  17
GLU A  18
 None
 1.27A 5nwuA-4lu1A:
undetectable		 5nwuA-4lu1A:
8.88