SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lu4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 8 ARG A  42
GLU A 161
GLN A 208
SER A 174
 None
 1.28A 1nx9A-4lu4A:
undetectable		 1nx9A-4lu4A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 8 ARG A  42
GLU A 161
GLN A 208
SER A 174
 None
 1.29A 1nx9B-4lu4A:
undetectable		 1nx9B-4lu4A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 8 ARG A  42
GLU A 161
GLN A 208
SER A 174
 None
 1.27A 1nx9C-4lu4A:
undetectable		 1nx9C-4lu4A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 8 ARG A  42
GLU A 161
GLN A 208
SER A 174
 None
 1.27A 1nx9D-4lu4A:
undetectable		 1nx9D-4lu4A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 8 SER A 127
PHE A 131
ALA A 135
LEU A 163
 None
 1.04A 2bxkA-4lu4A:
undetectable		 2bxkA-4lu4A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		3 / 3 ARG A 180
ASN A 134
THR A 205
 None
 0.78A 2q63A-4lu4A:
undetectable		 2q63A-4lu4A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 6 LEU A 123
ALA A 132
LEU A 126
SER A 127
 None
 1.05A 3cfqA-4lu4A:
undetectable		 3cfqA-4lu4A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 5 PHE A 173
ILE A 204
GLN A 156
ARG A 157
 None
None
None
IOD  A 307 ( 4.9A)
 1.39A 5jm4A-4lu4A:
undetectable		 5jm4A-4lu4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN
(Bartonella
quintana) 		4 / 4 PHE A 173
ILE A 204
GLN A 156
ARG A 157
 None
None
None
IOD  A 307 ( 4.9A)
 1.37A 5jm4B-4lu4A:
1.2		 5jm4B-4lu4A:
20.24