SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 TYR A  85
TYR A  15
GLU A  25
SER A 118
 None
 1.18A 1nx9A-4luaA:
undetectable		 1nx9A-4luaA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 TYR A  85
TYR A  15
GLU A  25
SER A 118
 None
 1.19A 1nx9B-4luaA:
undetectable		 1nx9B-4luaA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 TYR A  85
TYR A  15
GLU A  25
SER A 118
 None
 1.19A 1nx9C-4luaA:
2.3		 1nx9C-4luaA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 TYR A  85
TYR A  15
GLU A  25
SER A 118
 None
 1.21A 1nx9D-4luaA:
undetectable		 1nx9D-4luaA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 LEU A 116
THR A 117
TYR A 130
PHE A 129
ALA A  67
 None
 1.26A 3jusB-4luaA:
undetectable		 3jusB-4luaA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 TYR A  85
GLU A 154
ILE A 119
PHE A 135
THR A  27
 None
 1.15A 3ndiA-4luaA:
1.7		 3ndiA-4luaA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ILE A   4
LEU A  69
ALA A  68
ILE A 104
THR A   6
 None
 1.06A 4psyA-4luaA:
undetectable		 4psyA-4luaA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 ILE A  44
ILE A  41
PHE A  12
VAL A  54
THR A  66
 None
 1.30A 5lg3F-4luaA:
undetectable		 5lg3F-4luaA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4lua N-ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 ILE A  44
ILE A  41
PHE A  12
VAL A  54
THR A  66
 None
 1.27A 5lg3G-4luaA:
undetectable		 5lg3G-4luaA:
20.46