SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		4 / 5 ARG A  64
ASP A 173
SER A 174
SER A 269
 None
 1.47A 1kiaB-4lurA:
undetectable		 1kiaB-4lurA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		4 / 6 ARG A  64
ASP A 173
SER A 174
SER A 269
 None
 1.47A 1kiaC-4lurA:
undetectable		 1kiaC-4lurA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 12 ILE A 115
GLY A 116
GLY A 155
ILE A 156
ILE A 111
 None
 1.00A 2o4kA-4lurA:
undetectable		 2o4kA-4lurA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 12 ILE A 115
GLY A 116
GLY A 155
ILE A 156
ILE A 111
 None
 1.04A 2r5pA-4lurA:
undetectable		 2r5pA-4lurA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 12 ILE A 115
GLY A 116
GLY A 155
ILE A 156
ILE A 111
 None
 1.04A 2r5pC-4lurA:
undetectable		 2r5pC-4lurA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		3 / 3 GLY A 116
TYR A 158
SER A 154
 None
 0.76A 2xatA-4lurA:
undetectable		 2xatA-4lurA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		4 / 7 VAL A 275
ILE A 230
ILE A 205
THR A 211
 None
 0.88A 3deuA-4lurA:
undetectable		 3deuA-4lurA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 12 LEU A 109
VAL A  99
ILE A 101
GLY A 107
TYR A 197
 None
 1.31A 3hgiA-4lurA:
undetectable		 3hgiA-4lurA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 9 ASP A 217
ILE A 265
GLY A 267
ILE A 262
LEU A 186
 None
 1.15A 3u7sB-4lurA:
undetectable		 3u7sB-4lurA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 10 LEU A 153
ILE A 156
GLY A 155
GLY A 116
THR A 150
 None
 0.89A 4fakA-4lurA:
undetectable		 4fakA-4lurA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 11 ILE A 115
GLY A 155
ILE A 156
THR A 148
ILE A 111
 None
 0.93A 4njtA-4lurA:
undetectable		 4njtA-4lurA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 11 ILE A 115
GLY A 155
ILE A 156
THR A 148
ILE A 111
 None
 0.94A 4njvC-4lurA:
undetectable		 4njvC-4lurA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 11 GLY A 213
ALA A 215
ILE A 111
ILE A 159
GLY A 155
 GOL  A 403 (-3.6A)
None
None
None
None
 0.81A 4q1xA-4lurA:
undetectable		 4q1xA-4lurA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		4 / 4 THR A 211
GLY A 232
ASP A 280
SER A 208
 None
 1.39A 4rfqA-4lurA:
undetectable		 4rfqA-4lurA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 11 ILE A 115
GLY A 155
ILE A 156
THR A 148
ILE A 111
 None
 0.92A 4rvjA-4lurA:
undetectable		 4rvjA-4lurA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		5 / 11 ILE A 115
GLY A 155
ILE A 156
THR A 148
ILE A 111
 None
 0.92A 4rvjC-4lurA:
undetectable		 4rvjC-4lurA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		3 / 3 ASP A 133
LEU A 193
GLY A 194
 None
 0.46A 4xmfA-4lurA:
undetectable		 4xmfA-4lurA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 4lur INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN(IRBP)
(Danio
rerio) 		4 / 6 ILE A 204
LEU A 287
VAL A 231
ARG A 146
 None
 1.23A 6f6jA-4lurA:
undetectable		 6f6jA-4lurA:
undetectable