SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lvk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		4 / 4 HIS A 133
GLU A 129
HIS A 126
HIS A 135
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.1A)
MN  A 201 (-3.3A)
 1.20A 2hu6A-4lvkA:
undetectable		 2hu6A-4lvkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		4 / 4 HIS A 133
GLU A 129
HIS A 126
HIS A 135
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.1A)
MN  A 201 (-3.3A)
 1.15A 2ozrC-4lvkA:
undetectable		 2ozrC-4lvkA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		4 / 7 PHE A 104
GLY A 137
MET A   4
PHE A  92
 None
 1.12A 3ko0R-4lvkA:
undetectable
3ko0T-4lvkA:
undetectable		 3ko0R-4lvkA:
17.80
3ko0T-4lvkA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		4 / 4 HIS A 133
GLU A 129
HIS A 126
HIS A 135
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.1A)
MN  A 201 (-3.3A)
 1.21A 3lilA-4lvkA:
undetectable		 3lilA-4lvkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		5 / 12 GLY A 137
ALA A 121
ILE A  85
ASP A  81
GLN A 161
 None
 1.18A 4rtpA-4lvkA:
undetectable		 4rtpA-4lvkA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		5 / 12 LEU A  46
ASP A  96
PHE A 173
ILE A  84
PHE A 104
 None
 1.48A 5dlvA-4lvkA:
undetectable		 5dlvA-4lvkA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lvk PLASMID
RECOMBINATION ENZYME
(Streptococcus
agalactiae) 		5 / 12 THR A 106
ASP A 170
PHE A 173
PHE A  91
PHE A  92
 None
 1.49A 6iblB-4lvkA:
undetectable		 6iblB-4lvkA:
18.00