SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 TYR A 178
ILE A  41
GLY A 164
ALA A 183
GLY A 209
 None
 1.00A 1kiaA-4lvuA:
8.4		 1kiaA-4lvuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 TYR A 178
ILE A  41
GLY A 164
ALA A 183
GLY A 209
 None
 1.00A 1kiaB-4lvuA:
8.4		 1kiaB-4lvuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 TYR A 178
ILE A  41
GLY A 164
ALA A 183
GLY A 209
 None
 1.01A 1kiaC-4lvuA:
8.3		 1kiaC-4lvuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 TYR A 178
ILE A  41
GLY A 164
ALA A 183
GLY A 209
 None
 1.03A 1nbhB-4lvuA:
7.9		 1nbhB-4lvuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 TYR A 178
ILE A  41
GLY A 164
ALA A 183
GLY A 209
 None
 1.01A 1nbiA-4lvuA:
8.1		 1nbiA-4lvuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 TYR A 178
ILE A  41
GLY A 164
ALA A 183
GLY A 209
 None
 1.01A 1nbiB-4lvuA:
8.1		 1nbiB-4lvuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		6 / 11 GLY A  36
ALA A  38
ASP A  60
LEU A  61
ALA A 114
VAL A 136
 None
 0.56A 1uayA-4lvuA:
27.3		 1uayA-4lvuA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 8 LEU A  27
SER A  26
ALA A 109
ALA A 108
 None
 0.90A 3ax9B-4lvuA:
undetectable		 3ax9B-4lvuA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 12 GLY A 174
VAL A 125
ALA A 179
SER A 180
SER A 165
 None
 1.24A 3d91B-4lvuA:
undetectable		 3d91B-4lvuA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 5 SER A 165
ILE A  41
TYR A 178
GLY A 209
 None
 0.91A 3uboB-4lvuA:
6.7		 3uboB-4lvuA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 7 GLY A  53
ALA A  54
ALA A 253
ARG A  30
 None
 0.78A 3ur0B-4lvuA:
undetectable		 3ur0B-4lvuA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 6 THR A  39
GLY A  42
ILE A  34
LEU A  69
 None
 1.20A 4ac9C-4lvuA:
5.8		 4ac9C-4lvuA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 6 THR A  39
GLY A  42
ILE A  34
LEU A  69
 None
 1.21A 4acaC-4lvuA:
4.2		 4acaC-4lvuA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		3 / 3 ARG A 103
GLU A  79
ARG A  55
 None
 0.88A 4mwvA-4lvuA:
undetectable		 4mwvA-4lvuA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 5 THR A 189
THR A 205
THR A  35
HIS A 140
 None
 1.33A 4pgfB-4lvuA:
9.8		 4pgfB-4lvuA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 11 GLY A  36
GLY A  37
ASP A  60
LEU A  61
ASP A  86
 None
 0.75A 4pghA-4lvuA:
6.0		 4pghA-4lvuA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		5 / 11 LEU A  33
ASP A  60
ALA A  57
VAL A  46
ILE A  41
 None
 1.40A 4uuuA-4lvuA:
undetectable
4uuuB-4lvuA:
undetectable		 4uuuA-4lvuA:
21.40
4uuuB-4lvuA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4lvu OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY
(Burkholderia
thailandensis) 		4 / 5 THR A  39
GLY A  37
GLU A  47
HIS A  48
 None
 1.18A 5c0oH-4lvuA:
7.2		 5c0oH-4lvuA:
23.55