SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lw4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 4lw4 CYSTEINE
DESULFURATION
PROTEIN CSDE
(Escherichia
coli) 		3 / 3 ALA C  59
VAL C  65
TRP C  66
 None
 0.91A 1nt5A-4lw4C:
undetectable		 1nt5A-4lw4C:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 4lw4 CYSTEINE
DESULFURATION
PROTEIN CSDE
(Escherichia
coli) 		3 / 3 ALA C  59
VAL C  65
TRP C  66
 None
 0.91A 1nt5B-4lw4C:
undetectable		 1nt5B-4lw4C:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4lw4 CYSTEINE
DESULFURATION
PROTEIN CSDE
(Escherichia
coli) 		4 / 7 HIS C   9
LEU C  44
LEU C  96
LEU C  92
 None
 0.93A 3bgdB-4lw4C:
undetectable		 3bgdB-4lw4C:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 4lw4 CYSTEINE
DESULFURATION
PROTEIN CSDE
(Escherichia
coli) 		5 / 12 LEU C 133
GLY C 132
ASN C  63
ALA C  55
LEU C  47
 None
 1.02A 3vywC-4lw4C:
undetectable		 3vywC-4lw4C:
24.40