SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lx4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 6 LEU A 207
ASP A 210
MET A 266
LEU A 270
 None
 1.22A 1errB-4lx4A:
undetectable		 1errB-4lx4A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 ILE A 255
GLY A 254
MET A 310
HIS A  14
LEU A 273
 None
 1.45A 1fm6X-4lx4A:
undetectable		 1fm6X-4lx4A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.87A 1gtnB-4lx4A:
undetectable
1gtnC-4lx4A:
undetectable		 1gtnB-4lx4A:
13.42
1gtnC-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.92A 1gtnH-4lx4A:
undetectable
1gtnI-4lx4A:
undetectable		 1gtnH-4lx4A:
13.42
1gtnI-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 8 THR A 148
ALA A 155
GLY A 176
ALA A 156
 None
 0.68A 1gtnI-4lx4A:
undetectable
1gtnJ-4lx4A:
undetectable		 1gtnI-4lx4A:
13.42
1gtnJ-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 11 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.98A 1gtnM-4lx4A:
undetectable
1gtnN-4lx4A:
undetectable		 1gtnM-4lx4A:
13.42
1gtnN-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.98A 1gtnU-4lx4A:
undetectable
1gtnV-4lx4A:
undetectable		 1gtnU-4lx4A:
13.42
1gtnV-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifA-4lx4A:
undetectable		 1kifA-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifB-4lx4A:
undetectable		 1kifB-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifC-4lx4A:
undetectable		 1kifC-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifD-4lx4A:
undetectable		 1kifD-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifE-4lx4A:
undetectable		 1kifE-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifF-4lx4A:
undetectable		 1kifF-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifG-4lx4A:
undetectable		 1kifG-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1kifH-4lx4A:
undetectable		 1kifH-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.98A 1utdT-4lx4A:
undetectable
1utdU-4lx4A:
undetectable		 1utdT-4lx4A:
13.42
1utdU-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 1ve9A-4lx4A:
undetectable		 1ve9A-4lx4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 ILE A 296
ALA A 295
ILE A  55
ILE A  52
TYR A  47
 None
 1.14A 2dm6A-4lx4A:
undetectable
2dm6B-4lx4A:
undetectable		 2dm6A-4lx4A:
19.78
2dm6B-4lx4A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  46
TYR A  47
ILE A 296
GLY A 301
 None
 1.31A 2du8J-4lx4A:
undetectable		 2du8J-4lx4A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 LEU A 207
ASP A 210
MET A 266
LEU A 270
 None
 1.20A 2jfaA-4lx4A:
undetectable		 2jfaA-4lx4A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 8 LEU A 309
SER A 280
VAL A 231
GLY A 230
 None
 0.72A 2qd5A-4lx4A:
1.7		 2qd5A-4lx4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 8 LEU A 309
SER A 280
VAL A 231
GLY A 230
 None
 0.68A 2qd5B-4lx4A:
undetectable		 2qd5B-4lx4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 LEU A 207
ASP A 210
MET A 266
LEU A 270
 None
 1.27A 2qxsA-4lx4A:
undetectable		 2qxsA-4lx4A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 LEU A 207
ASP A 210
MET A 266
LEU A 270
 None
 1.26A 2qxsB-4lx4A:
undetectable		 2qxsB-4lx4A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		6 / 12 ASN A 143
GLU A 144
HIS A 206
TYR A 208
GLU A 252
TRP A 283
 TRS  A 401 (-2.5A)
TRS  A 401 (-1.8A)
TRS  A 401 ( 4.8A)
TRS  A 401 ( 4.9A)
TRS  A 401 (-2.6A)
TRS  A 401 ( 3.4A)
 0.79A 2v3dA-4lx4A:
17.7		 2v3dA-4lx4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 11 ASN A 143
GLU A 144
TYR A 208
GLU A 252
TRP A 283
 TRS  A 401 (-2.5A)
TRS  A 401 (-1.8A)
TRS  A 401 ( 4.9A)
TRS  A 401 (-2.6A)
TRS  A 401 ( 3.4A)
 0.89A 2v3dB-4lx4A:
2.2		 2v3dB-4lx4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 8 TYR A 217
ILE A 255
GLY A 254
LEU A 250
 None
 0.89A 2vctB-4lx4A:
undetectable		 2vctB-4lx4A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 8 TYR A 217
ILE A 255
GLY A 254
LEU A 250
 None
 0.90A 2vctC-4lx4A:
undetectable		 2vctC-4lx4A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 7 TYR A 217
ILE A 255
GLY A 254
LEU A 250
 None
 0.91A 2vctD-4lx4A:
undetectable		 2vctD-4lx4A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 8 GLY A 176
ILE A 141
HIS A 206
GLU A 204
 None
None
TRS  A 401 ( 4.8A)
None
 0.93A 2x0pA-4lx4A:
undetectable		 2x0pA-4lx4A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 ASP A  97
GLY A 138
LEU A 171
VAL A 160
ILE A 141
 None
 1.02A 3em4V-4lx4A:
undetectable		 3em4V-4lx4A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 GLU A 175
ALA A 205
GLY A 251
LEU A 207
GLY A 248
 None
 1.08A 3g2oA-4lx4A:
undetectable		 3g2oA-4lx4A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 GLU A 175
ALA A 205
GLY A 251
LEU A 207
GLY A 248
 None
 1.06A 3g2oB-4lx4A:
undetectable		 3g2oB-4lx4A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		3 / 3 ASN A  17
ASP A  97
ARG A 178
 None
 0.89A 3k13A-4lx4A:
8.1		 3k13A-4lx4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 11 GLU A 144
GLY A 176
ILE A 174
GLU A 175
ALA A 156
 TRS  A 401 (-1.8A)
None
None
None
None
 1.11A 3nmuB-4lx4A:
undetectable
3nmuJ-4lx4A:
undetectable		 3nmuB-4lx4A:
21.60
3nmuJ-4lx4A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 7 ALA A 281
HIS A  14
PRO A 279
LEU A 250
 None
 1.00A 5dzkD-4lx4A:
2.6
5dzkR-4lx4A:
undetectable		 5dzkD-4lx4A:
22.12
5dzkR-4lx4A:
2.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.92A 5eeuF-4lx4A:
undetectable
5eeuG-4lx4A:
undetectable		 5eeuF-4lx4A:
13.42
5eeuG-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.89A 5eeuI-4lx4A:
undetectable
5eeuJ-4lx4A:
undetectable		 5eeuI-4lx4A:
13.42
5eeuJ-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5eeuO-4lx4A:
undetectable
5eeuP-4lx4A:
undetectable		 5eeuO-4lx4A:
13.42
5eeuP-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.94A 5eeuQ-4lx4A:
undetectable
5eeuR-4lx4A:
undetectable		 5eeuQ-4lx4A:
13.42
5eeuR-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5eevF-4lx4A:
undetectable
5eevG-4lx4A:
undetectable		 5eevF-4lx4A:
13.42
5eevG-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.89A 5eevI-4lx4A:
undetectable
5eevJ-4lx4A:
undetectable		 5eevI-4lx4A:
13.42
5eevJ-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.96A 5eevO-4lx4A:
undetectable
5eevP-4lx4A:
undetectable		 5eevO-4lx4A:
13.42
5eevP-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5eevQ-4lx4A:
undetectable
5eevR-4lx4A:
undetectable		 5eevQ-4lx4A:
13.42
5eevR-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5eewF-4lx4A:
undetectable
5eewG-4lx4A:
undetectable		 5eewF-4lx4A:
13.42
5eewG-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.89A 5eewI-4lx4A:
undetectable
5eewJ-4lx4A:
undetectable		 5eewI-4lx4A:
13.42
5eewJ-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.96A 5eewO-4lx4A:
undetectable
5eewP-4lx4A:
undetectable		 5eewO-4lx4A:
13.42
5eewP-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5eewQ-4lx4A:
undetectable
5eewR-4lx4A:
undetectable		 5eewQ-4lx4A:
13.42
5eewR-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5eexF-4lx4A:
undetectable
5eexG-4lx4A:
undetectable		 5eexF-4lx4A:
13.42
5eexG-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.96A 5eexO-4lx4A:
undetectable
5eexP-4lx4A:
undetectable		 5eexO-4lx4A:
13.42
5eexP-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5eeyF-4lx4A:
undetectable
5eeyG-4lx4A:
undetectable		 5eeyF-4lx4A:
13.42
5eeyG-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5eeyO-4lx4A:
undetectable
5eeyP-4lx4A:
undetectable		 5eeyO-4lx4A:
13.42
5eeyP-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5eezF-4lx4A:
undetectable
5eezG-4lx4A:
undetectable		 5eezF-4lx4A:
13.42
5eezG-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.96A 5eezO-4lx4A:
undetectable
5eezP-4lx4A:
undetectable		 5eezO-4lx4A:
13.42
5eezP-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5ef0F-4lx4A:
undetectable
5ef0G-4lx4A:
undetectable		 5ef0F-4lx4A:
13.42
5ef0G-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.96A 5ef0O-4lx4A:
undetectable
5ef0P-4lx4A:
undetectable		 5ef0O-4lx4A:
13.42
5ef0P-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5ef1F-4lx4A:
undetectable
5ef1G-4lx4A:
undetectable		 5ef1F-4lx4A:
13.42
5ef1G-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5ef1O-4lx4A:
undetectable
5ef1P-4lx4A:
undetectable		 5ef1O-4lx4A:
13.42
5ef1P-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5ef2F-4lx4A:
undetectable
5ef2G-4lx4A:
undetectable		 5ef2F-4lx4A:
13.42
5ef2G-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5ef2O-4lx4A:
undetectable
5ef2P-4lx4A:
undetectable		 5ef2O-4lx4A:
13.42
5ef2P-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 THR A 148
ALA A 155
GLY A 176
ALA A 156
ILE A 174
 None
 0.93A 5ef3F-4lx4A:
undetectable
5ef3G-4lx4A:
undetectable		 5ef3F-4lx4A:
13.42
5ef3G-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 10 GLY A 176
ALA A 156
ILE A 174
THR A 148
ALA A 155
 None
 0.95A 5ef3O-4lx4A:
undetectable
5ef3P-4lx4A:
undetectable		 5ef3O-4lx4A:
13.42
5ef3P-4lx4A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 ILE A 202
ALA A 155
ALA A 156
VAL A 160
GLY A 102
 None
 0.82A 5igjA-4lx4A:
undetectable		 5igjA-4lx4A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 ILE A 202
ALA A 155
ALA A 156
VAL A 160
GLY A 102
 None
 0.81A 5igtA-4lx4A:
undetectable		 5igtA-4lx4A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 GLY A  51
GLU A 252
ALA A  87
ILE A 296
MET A 307
 None
TRS  A 401 (-2.6A)
None
None
None
 1.17A 5igyA-4lx4A:
undetectable		 5igyA-4lx4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 LEU A  13
PRO A   4
GLY A  15
ILE A 321
PRO A 279
 None
 1.09A 5wyqA-4lx4A:
undetectable		 5wyqA-4lx4A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		5 / 12 LEU A 250
GLY A 251
HIS A 206
ARG A  56
ILE A  55
 None
None
TRS  A 401 ( 4.8A)
TRS  A 401 ( 4.6A)
None
 1.41A 6bxnB-4lx4A:
undetectable		 6bxnB-4lx4A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN
(Pseudomonas
stutzeri) 		4 / 5 TYR A  47
GLN A  92
GLY A 254
ILE A 296
 None
 1.40A 6debB-4lx4A:
undetectable		 6debB-4lx4A:
14.53