SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ly4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.42A 1grmA-4ly4A:
undetectable		 1grmA-4ly4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.42A 1grmB-4ly4A:
undetectable		 1grmB-4ly4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.64A 1jo3A-4ly4A:
undetectable		 1jo3A-4ly4A:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.64A 1jo3B-4ly4A:
undetectable		 1jo3B-4ly4A:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.50A 1jo4A-4ly4A:
undetectable		 1jo4A-4ly4A:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.50A 1jo4B-4ly4A:
undetectable		 1jo4B-4ly4A:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.67A 1ng8A-4ly4A:
undetectable		 1ng8A-4ly4A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.67A 1ng8B-4ly4A:
undetectable		 1ng8B-4ly4A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.68A 1nrmA-4ly4A:
undetectable		 1nrmA-4ly4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.69A 1nrmB-4ly4A:
undetectable		 1nrmB-4ly4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.66A 1nruA-4ly4A:
undetectable		 1nruA-4ly4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ALA A  57
VAL A 276
TRP A 275
 None
 0.66A 1nruB-4ly4A:
undetectable		 1nruB-4ly4A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ASP A  14
HIS A  86
HIS A  90
 ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
 0.60A 1oe1A-4ly4A:
undetectable		 1oe1A-4ly4A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ASP A  14
HIS A  86
HIS A  90
 ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
 0.60A 1oe3A-4ly4A:
undetectable		 1oe3A-4ly4A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 8 VAL A 256
ASP A 199
HIS A 260
LEU A  49
 None
 1.23A 1pk2A-4ly4A:
undetectable		 1pk2A-4ly4A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.23A 2eimJ-4ly4A:
undetectable		 2eimJ-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.29A 2eimW-4ly4A:
undetectable		 2eimW-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 SER A 251
HIS A  86
ASP A 146
 None
ZN  A 301 (-3.4A)
None
 0.81A 2oxtA-4ly4A:
undetectable		 2oxtA-4ly4A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 9 LEU A 257
LEU A  47
VAL A  11
GLY A  10
MET A 244
 None
 1.46A 2po7A-4ly4A:
0.5		 2po7A-4ly4A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 GLN A 229
THR A 245
TRP A 196
 None
 1.03A 2rctA-4ly4A:
undetectable		 2rctA-4ly4A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ASP A  14
HIS A  86
HIS A  90
 ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
 0.60A 2xxgA-4ly4A:
undetectable		 2xxgA-4ly4A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 ASP A  14
HIS A  86
HIS A  90
 ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
 0.62A 2xxgC-4ly4A:
undetectable		 2xxgC-4ly4A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.24A 3ag2J-4ly4A:
undetectable		 3ag2J-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.25A 3ag4J-4ly4A:
undetectable		 3ag4J-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 8 ILE A 192
TYR A 145
ALA A   8
PRO A  56
 None
 0.81A 3ozwA-4ly4A:
undetectable		 3ozwA-4ly4A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 7 HIS A 147
GLU A 191
ALA A 125
PHE A 130
 None
 0.78A 3tehB-4ly4A:
undetectable		 3tehB-4ly4A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 11 HIS A 247
SER A 243
PHE A 278
GLY A  84
ASN A 279
 None
 1.48A 3v3nA-4ly4A:
undetectable		 3v3nA-4ly4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 11 HIS A 247
SER A 243
PHE A 278
GLY A  84
ASN A 279
 None
 1.49A 3v3nD-4ly4A:
undetectable		 3v3nD-4ly4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 12 PHE A  50
ILE A  13
GLY A  42
ALA A 252
VAL A  11
 None
 1.14A 4nkvA-4ly4A:
undetectable		 4nkvA-4ly4A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 12 PHE A  50
ILE A  13
GLY A  42
ALA A 252
VAL A  11
 None
 1.14A 4nkvC-4ly4A:
undetectable		 4nkvC-4ly4A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 12 PHE A  50
ILE A  13
GLY A  42
ALA A 252
VAL A  11
 None
 1.12A 4nkvD-4ly4A:
undetectable		 4nkvD-4ly4A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 8 ILE A  94
ASN A  92
ALA A  95
TRP A 127
 None
 0.99A 4ou1A-4ly4A:
2.8		 4ou1A-4ly4A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 6 LEU A 111
PRO A  70
PHE A  69
GLU A  40
 None
 1.28A 5b8iA-4ly4A:
undetectable		 5b8iA-4ly4A:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 8 HIS A 247
SER A  65
HIS A  86
HIS A  90
 None
None
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
 0.98A 5m8rB-4ly4A:
undetectable		 5m8rB-4ly4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 8 HIS A 247
SER A  65
HIS A  86
HIS A  90
 None
None
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
 0.97A 5m8rD-4ly4A:
undetectable		 5m8rD-4ly4A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 6 ASP A  12
ASP A  14
HIS A  86
HIS A  90
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
 0.71A 5ncdA-4ly4A:
15.8
5ncdD-4ly4A:
16.0		 5ncdA-4ly4A:
23.62
5ncdD-4ly4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 6 ASP A  12
ASP A  14
HIS A  86
HIS A  90
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
 0.72A 5ncdB-4ly4A:
15.8
5ncdC-4ly4A:
15.9		 5ncdB-4ly4A:
23.62
5ncdC-4ly4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 4 ASP A  12
HIS A  86
HIS A  90
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
 0.30A 5ncdD-4ly4A:
16.0		 5ncdD-4ly4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		6 / 8 ASP A  12
ASP A  14
HIS A  86
HIS A  90
PRO A 126
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
None
 0.65A 5nekB-4ly4A:
15.9		 5nekB-4ly4A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 8 ASP A  12
ASP A  14
HIS A  86
HIS A  90
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
 0.67A 5nekD-4ly4A:
15.8		 5nekD-4ly4A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		5 / 6 ASP A  12
ASP A  14
HIS A  86
HIS A  90
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-2.1A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
 0.65A 5nelA-4ly4A:
15.8
5nelD-4ly4A:
4.5		 5nelA-4ly4A:
23.62
5nelD-4ly4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 6 ASP A  12
HIS A  86
HIS A  90
HIS A 247
 ZN  A 301 (-4.6A)
ZN  A 301 (-3.4A)
ZN  A 301 (-3.4A)
None
 0.30A 5nelB-4ly4A:
15.8
5nelC-4ly4A:
15.8		 5nelB-4ly4A:
23.62
5nelC-4ly4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.18A 5wauJ-4ly4A:
undetectable		 5wauJ-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.18A 5x1bW-4ly4A:
undetectable		 5x1bW-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.24A 5z86J-4ly4A:
undetectable		 5z86J-4ly4A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		3 / 3 TRP A 165
ILE A 182
ASP A 163
 None
 0.86A 6i0y7-4ly4A:
undetectable		 6i0y7-4ly4A:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4ly4 PEPTIDOGLYCAN
DEACETYLASE
(Helicobacter
pylori) 		4 / 5 TYR A   9
MET A 244
THR A 245
LEU A 198
 None
 1.23A 6nknW-4ly4A:
undetectable		 6nknW-4ly4A:
10.43