SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ly7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 4ly7 RIBONUCLEASE H
(unidentified) 		3 / 4 VAL A 101
TRP A  81
TRP A  90
 None
 1.23A 1gmkC-4ly7A:
undetectable
1gmkD-4ly7A:
undetectable		 1gmkC-4ly7A:
10.26
1gmkD-4ly7A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 4ly7 RIBONUCLEASE H
(unidentified) 		3 / 3 GLN A  72
THR A   9
TRP A 118
 None
 0.94A 2rctA-4ly7A:
undetectable		 2rctA-4ly7A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 4ly7 RIBONUCLEASE H
(unidentified) 		5 / 10 LEU A  59
LEU A  56
SER A  68
LEU A  67
TRP A 118
 None
 0.98A 4yiaA-4ly7A:
undetectable		 4yiaA-4ly7A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 4ly7 RIBONUCLEASE H
(unidentified) 		5 / 12 ALA A  52
GLU A   6
LEU A  26
ILE A  25
ARG A 132
 None
 1.28A 5vlmE-4ly7A:
undetectable		 5vlmE-4ly7A:
22.61