SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lzk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4lzk PIXA INCLUSION BODY
PROTEIN
(Burkholderia
cenocepacia) 		3 / 3 VAL A 178
ALA A 156
HIS A  98
 None
 0.69A 1q23L-4lzkA:
undetectable		 1q23L-4lzkA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4lzk PIXA INCLUSION BODY
PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 VAL A  79
PHE A 111
VAL A  99
LEU A 155
THR A 157
 None
 1.05A 2jn3A-4lzkA:
undetectable		 2jn3A-4lzkA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4lzk PIXA INCLUSION BODY
PROTEIN
(Burkholderia
cenocepacia) 		4 / 8 ILE A  96
GLY A  83
LEU A  20
LEU A  53
 None
 0.86A 2vctA-4lzkA:
undetectable		 2vctA-4lzkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4lzk PIXA INCLUSION BODY
PROTEIN
(Burkholderia
cenocepacia) 		4 / 8 ILE A  96
GLY A  83
LEU A  20
LEU A  53
 None
 0.86A 2vctB-4lzkA:
undetectable		 2vctB-4lzkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4lzk PIXA INCLUSION BODY
PROTEIN
(Burkholderia
cenocepacia) 		4 / 8 ILE A  96
GLY A  83
LEU A  20
LEU A  53
 None
 0.83A 2vctC-4lzkA:
undetectable		 2vctC-4lzkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4lzk PIXA INCLUSION BODY
PROTEIN
(Burkholderia
cenocepacia) 		4 / 5 PHE A 172
TYR A  27
ILE A  96
LEU A  95
 None
 1.31A 3sueC-4lzkA:
undetectable		 3sueC-4lzkA:
22.69