SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lzl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA205_1 (CARDIAC TROPONIN C)	4lzl	RESPONSE REGULATOR (Streptococcus pneumoniae)	5 / 12	ILE A 117 PHE A 118 LEU A 22 LEU A 80 MET A 78	None	1.03A	1dtlA-4lzlA: undetectable	1dtlA-4lzlA: 25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P5N_A_RBFA190_1 (RIBOFLAVIN UPTAKE PROTEIN)	4lzl	RESPONSE REGULATOR (Streptococcus pneumoniae)	5 / 12	ASP A 58 GLY A 35 ALA A 38 ALA A 42 LEU A 6	None	1.01A	3p5nA-4lzlA: undetectable	3p5nA-4lzlA: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P5N_B_RBFB190_1 (RIBOFLAVIN UPTAKE PROTEIN)	4lzl	RESPONSE REGULATOR (Streptococcus pneumoniae)	5 / 12	ASP A 58 GLY A 35 ALA A 38 ALA A 42 LEU A 6	None	1.02A	3p5nB-4lzlA: undetectable	3p5nB-4lzlA: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC0_A_RBFA303_1 (RIBOFLAVIN TRANSPORTER RIBU)	4lzl	RESPONSE REGULATOR (Streptococcus pneumoniae)	5 / 12	GLU A 9 LEU A 56 LYS A 103 ASP A 81 ALA A 65	None None None None GOL A 301 (-3.5A)	1.28A	5kc0A-4lzlA: undetectable	5kc0A-4lzlA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_B_CVIB301_0 (REGULATORY PROTEIN TETR)	4lzl	RESPONSE REGULATOR (Streptococcus pneumoniae)	5 / 12	ALA A 15 GLU A 21 LEU A 110 ILE A 114 VAL A 29	None	0.92A	5vlmB-4lzlA: undetectable	5vlmB-4lzlA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA205_1","CARDIAC TROPONIN C","4lzl","RESPONSE REGULATOR","Streptococcus pneumoniae",5,"ILE A 117;PHE A 118;LEU A  22;LEU A  80;MET A  78","None","1.03A","1dtlA-4lzlA:undetectable","1dtlA-4lzlA:25.95"],["3P5N_A_RBFA190_1","RIBOFLAVIN UPTAKE PROTEIN","4lzl","RESPONSE REGULATOR","Streptococcus pneumoniae",5,"ASP A  58;GLY A  35;ALA A  38;ALA A  42;LEU A   6","None","1.01A","3p5nA-4lzlA:undetectable","3p5nA-4lzlA:22.56"],["3P5N_B_RBFB190_1","RIBOFLAVIN UPTAKE PROTEIN","4lzl","RESPONSE REGULATOR","Streptococcus pneumoniae",5,"ASP A  58;GLY A  35;ALA A  38;ALA A  42;LEU A   6","None","1.02A","3p5nB-4lzlA:undetectable","3p5nB-4lzlA:22.56"],["5KC0_A_RBFA303_1","RIBOFLAVIN TRANSPORTER RIBU","4lzl","RESPONSE REGULATOR","Streptococcus pneumoniae",5,"GLU A   9;LEU A  56;LYS A 103;ASP A  81;ALA A  65","None;None;None;None;GOL A 301 (-3.5A)","1.28A","5kc0A-4lzlA:undetectable","5kc0A-4lzlA:20.00"],["5VLM_B_CVIB301_0","REGULATORY PROTEIN TETR","4lzl","RESPONSE REGULATOR","Streptococcus pneumoniae",5,"ALA A  15;GLU A  21;LEU A 110;ILE A 114;VAL A  29","None","0.92A","5vlmB-4lzlA:undetectable","5vlmB-4lzlA:21.43"]]