SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lzp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 4lzp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Brucella
melitensis) 		4 / 6 THR B 222
SER B 250
SER B 248
VAL B 244
 None
 1.32A 2hdnI-4lzpB:
undetectable
2hdnJ-4lzpB:
undetectable
2hdnL-4lzpB:
2.8		 2hdnI-4lzpB:
14.78
2hdnJ-4lzpB:
17.70
2hdnL-4lzpB:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 4lzp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Brucella
melitensis) 		4 / 6 SER B 248
VAL B 244
THR B 222
SER B 250
 None
 1.25A 2hdnJ-4lzpB:
undetectable
2hdnK-4lzpB:
undetectable
2hdnL-4lzpB:
2.8		 2hdnJ-4lzpB:
17.70
2hdnK-4lzpB:
14.78
2hdnL-4lzpB:
17.70