SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m00'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.23A 1rs6B-4m00A:
undetectable		 1rs6B-4m00A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.25A 1zzqB-4m00A:
undetectable		 1zzqB-4m00A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 7 GLY A 603
THR A 604
ASP A 601
ASN A 602
 CA  A 802 ( 4.4A)
None
CA  A 802 (-2.2A)
CA  A 802 (-3.0A)
 0.98A 2g70A-4m00A:
undetectable		 2g70A-4m00A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 7 GLY A 603
THR A 604
ASP A 601
ASN A 602
 CA  A 802 ( 4.4A)
None
CA  A 802 (-2.2A)
CA  A 802 (-3.0A)
 0.98A 2g70B-4m00A:
undetectable		 2g70B-4m00A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 328
GLY A 329
ASN A 480
ALA A 473
GLY A 319
 None
 1.05A 2pkkA-4m00A:
undetectable		 2pkkA-4m00A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 SER A 309
TYR A 435
HIS A 311
 None
 0.46A 2r2vD-4m00A:
undetectable		 2r2vD-4m00A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 THR A 412
SER A 411
PHE A 395
 None
 0.87A 3d4sA-4m00A:
undetectable		 3d4sA-4m00A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.97A 3eluA-4m00A:
undetectable		 3eluA-4m00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.98A 3embA-4m00A:
undetectable		 3embA-4m00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.98A 3gczA-4m00A:
undetectable		 3gczA-4m00A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.29A 3n66B-4m00A:
undetectable		 3n66B-4m00A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 TYR A 446
ILE A 332
VAL A 316
ILE A 433
 None
 0.77A 3p4wC-4m00A:
undetectable		 3p4wC-4m00A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 ASN A 649
ALA A 576
LYS A 575
 CA  A 802 ( 4.7A)
None
None
 0.93A 3runA-4m00A:
undetectable		 3runA-4m00A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 LEU A 614
PRO A 615
LEU A 618
 None
 0.48A 3w1wB-4m00A:
undetectable		 3w1wB-4m00A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tA-4m00A:
undetectable		 3w9tA-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tB-4m00A:
undetectable		 3w9tB-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tC-4m00A:
undetectable		 3w9tC-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tD-4m00A:
undetectable		 3w9tD-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tE-4m00A:
undetectable		 3w9tE-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 6 THR A 479
ASN A 480
GLY A 331
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.17A 3w9tE-4m00A:
undetectable		 3w9tE-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tF-4m00A:
undetectable		 3w9tF-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 ASP A 573
VAL A 574
GLY A 537
ASP A 601
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-2.2A)
 1.46A 3w9tG-4m00A:
undetectable		 3w9tG-4m00A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 7 ASN A 374
ALA A 376
SER A 375
VAL A 403
 None
 1.14A 4ijiH-4m00A:
undetectable		 4ijiH-4m00A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 7 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.26A 4kcnB-4m00A:
undetectable		 4kcnB-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 THR A 505
THR A 506
ASP A 503
TYR A 538
 None
 1.25A 4oltA-4m00A:
undetectable		 4oltA-4m00A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 THR A 505
THR A 506
ASP A 503
TYR A 538
 None
 1.23A 4oltB-4m00A:
undetectable		 4oltB-4m00A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 THR A 505
THR A 506
ASP A 503
TYR A 538
 None
 1.23A 4qwpA-4m00A:
undetectable		 4qwpA-4m00A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 THR A 505
THR A 506
ASP A 503
TYR A 538
 None
 1.25A 4qwpB-4m00A:
undetectable		 4qwpB-4m00A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.99A 5ehiA-4m00A:
undetectable		 5ehiA-4m00A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.97A 5ehiC-4m00A:
undetectable		 5ehiC-4m00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.99A 5eiwA-4m00A:
undetectable		 5eiwA-4m00A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.97A 5ekxA-4m00A:
undetectable		 5ekxA-4m00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 7 THR A 505
ASP A 503
TYR A 538
GLY A 603
 None
None
None
CA  A 802 ( 4.4A)
 1.06A 5hwaA-4m00A:
undetectable		 5hwaA-4m00A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 ALA A 349
PHE A 362
GLY A 361
GLY A 354
GLY A 393
 MES  A 805 ( 4.9A)
None
None
None
None
 0.94A 5i71A-4m00A:
undetectable		 5i71A-4m00A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 ALA A 349
PHE A 362
GLY A 361
GLY A 354
GLY A 393
 MES  A 805 ( 4.9A)
None
None
None
None
 0.98A 5i73A-4m00A:
undetectable		 5i73A-4m00A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.97A 5kqrA-4m00A:
undetectable		 5kqrA-4m00A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 10 TYR A 446
ILE A 332
MET A 471
VAL A 316
ILE A 433
 None
 1.04A 5mzrA-4m00A:
undetectable		 5mzrA-4m00A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 10 TYR A 446
ILE A 332
MET A 471
VAL A 316
ILE A 433
 None
 1.02A 5mzrC-4m00A:
undetectable		 5mzrC-4m00A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 SER A 549
ALA A 548
THR A 497
 None
 0.69A 5n0xB-4m00A:
undetectable		 5n0xB-4m00A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 GLY A 331
GLY A 329
GLY A 476
THR A 366
ILE A 332
 None
None
SUC  A 804 (-3.4A)
None
None
 0.93A 5njvC-4m00A:
undetectable		 5njvC-4m00A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 6 TYR A 569
TYR A 501
ASP A 544
TYR A 516
 None
 1.48A 5ov9A-4m00A:
undetectable		 5ov9A-4m00A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 7 TYR A 569
TYR A 501
ASP A 544
TYR A 516
 None
 1.44A 5ov9B-4m00A:
undetectable		 5ov9B-4m00A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.27A 5vunA-4m00A:
undetectable		 5vunA-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.20A 5vunB-4m00A:
undetectable		 5vunB-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.21A 5vuoB-4m00A:
undetectable		 5vuoB-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 ALA A 495
GLY A 564
THR A 255
LEU A 341
ASN A 562
 None
 1.18A 5ybbA-4m00A:
undetectable		 5ybbA-4m00A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.18A 6auuB-4m00A:
undetectable		 6auuB-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 TYR A 446
ALA A 391
LEU A 318
 None
 0.68A 6d9kF-4m00A:
undetectable		 6d9kF-4m00A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 GLN A 565
THR A 497
LYS A 514
SER A 494
 None
 1.06A 6fbvC-4m00A:
undetectable		 6fbvC-4m00A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 4 ASP A 573
SER A 643
SER A 651
ASN A 602
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-3.0A)
 1.46A 6iblA-4m00A:
0.0		 6iblA-4m00A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 4 ASP A 573
SER A 643
SER A 651
ASN A 602
 CA  A 802 (-2.1A)
None
None
CA  A 802 (-3.0A)
 1.46A 6iblB-4m00A:
0.0		 6iblB-4m00A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4m00 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 THR A 479
GLU A 323
ASN A 327
 None
 0.85A 6nj9K-4m00A:
undetectable		 6nj9K-4m00A:
20.54