SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m03'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 5 LEU A 156
PRO A 157
LEU A 160
ILE A 169
 None
 0.87A 2qd4A-4m03A:
undetectable		 2qd4A-4m03A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 LEU A 156
PRO A 157
LEU A 160
 None
 0.49A 2qd5B-4m03A:
undetectable		 2qd5B-4m03A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		5 / 12 ILE A 212
ASN A 240
THR A 208
VAL A 242
THR A 284
 None
 1.18A 3dcjA-4m03A:
undetectable
3dcjB-4m03A:
undetectable		 3dcjA-4m03A:
19.49
3dcjB-4m03A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ILE A 137
LEU A 156
ASN A 151
VAL A 153
 None
 0.78A 3dcjB-4m03A:
undetectable		 3dcjB-4m03A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 LEU A 245
ASN A 240
THR A 210
VAL A 242
 None
 0.84A 3dcjB-4m03A:
undetectable		 3dcjB-4m03A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 LEU A 156
PRO A 157
LEU A 160
 None
 0.44A 3w1wB-4m03A:
undetectable		 3w1wB-4m03A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		3 / 3 LEU A 245
PRO A 246
LEU A 249
 None
 0.48A 3w1wB-4m03A:
undetectable		 3w1wB-4m03A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 8 ILE A 228
ILE A 270
LEU A 245
ILE A 258
 None
 0.93A 4dtaB-4m03A:
undetectable		 4dtaB-4m03A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4m03 SERINE-RICH ADHESIN
FOR PLATELETS
(Staphylococcus
aureus) 		4 / 4 LEU A 156
PRO A 157
LEU A 160
ILE A 169
 None
 0.94A 4f4dB-4m03A:
undetectable		 4f4dB-4m03A:
20.81