SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		5 / 12 LEU A 147
LEU A 145
ALA A 116
ALA A 118
VAL A  22
 None
 1.22A 1kt4A-4m0qA:
undetectable		 1kt4A-4m0qA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		5 / 11 LEU A 152
ILE A 153
ASN A 156
GLY A 101
LEU A 119
 None
 1.11A 2bxeA-4m0qA:
undetectable		 2bxeA-4m0qA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		5 / 12 LEU A 152
ILE A 153
ASN A 156
GLY A 101
LEU A 119
 None
 1.05A 2bxeB-4m0qA:
undetectable		 2bxeB-4m0qA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		3 / 3 GLN A  33
THR A  34
LEU A  94
 None
 0.56A 3ondA-4m0qA:
undetectable		 3ondA-4m0qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		3 / 3 GLN A  33
THR A  34
LEU A  94
 None
 0.58A 3ondB-4m0qA:
undetectable		 3ondB-4m0qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		3 / 3 LEU A  57
HIS A  58
MET A  54
 None
 0.93A 3thrD-4m0qA:
undetectable		 3thrD-4m0qA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		5 / 11 ILE A 188
ALA A 100
GLY A 101
GLY A 120
HIS A 186
 None
 1.29A 4jdsC-4m0qA:
undetectable		 4jdsC-4m0qA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		5 / 12 ILE A 188
ALA A 100
GLY A 101
GLY A 120
HIS A 186
 None
 1.25A 4jlgA-4m0qA:
undetectable		 4jlgA-4m0qA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		4 / 6 ILE A 157
GLN A 105
ILE A 107
ASP A 108
 None
 0.98A 4w5tA-4m0qA:
undetectable		 4w5tA-4m0qA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		4 / 4 GLN A  33
THR A  34
LEU A  94
LEU A  91
 None
 1.18A 5m5kB-4m0qA:
undetectable		 5m5kB-4m0qA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		3 / 3 CYH A  27
MET A 136
ASN A 135
 None
 1.23A 5qh8A-4m0qA:
undetectable		 5qh8A-4m0qA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 4m0q MEMBRANE-ASSOCIATED
PROTEIN VP24
(Zaire
ebolavirus) 		4 / 6 ILE A 157
GLN A 105
ILE A 107
ASP A 108
 None
 1.01A 6cbdA-4m0qA:
undetectable		 6cbdA-4m0qA:
13.40