SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_A_NOVA400_2 (DNA GYRASE SUBUNIT B)	4m18	PULMONARY SURFACTANT-ASSOCIATE D PROTEIN D (Homo sapiens)	3 / 3	ASN A 341 PHE A 292 VAL A 343	MAN A 406 ( 2.6A) None MAN A 406 ( 4.7A)	0.60A	1kijA-4m18A: undetectable	1kijA-4m18A: 17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCR_A_CHDA424_0 (FERROCHELATASE, MITOCHONDRIAL)	4m18	PULMONARY SURFACTANT-ASSOCIATE D PROTEIN D (Homo sapiens)	4 / 8	LEU A 268 ARG A 349 SER A 298 GLY A 346	None MAN A 407 (-3.9A) None None	1.16A	3hcrA-4m18A: undetectable	3hcrA-4m18A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCR_B_CHDB924_0 (FERROCHELATASE, MITOCHONDRIAL)	4m18	PULMONARY SURFACTANT-ASSOCIATE D PROTEIN D (Homo sapiens)	4 / 7	LEU A 268 ARG A 349 SER A 298 GLY A 346	None MAN A 407 (-3.9A) None None	1.05A	3hcrB-4m18A: undetectable	3hcrB-4m18A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MDB_A_RLTA401_1 (MARINER MOS1 TRANSPOSASE)	4m18	PULMONARY SURFACTANT-ASSOCIATE D PROTEIN D (Homo sapiens)	4 / 6	ASP A 297 ASN A 323 ALA A 325 ASP A 330	CA A 402 (-2.2A) MAN A 406 ( 2.6A) MAN A 405 ( 3.7A) CA A 403 ( 2.2A)	1.06A	4mdbA-4m18A: undetectable	4mdbA-4m18A: 20.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KIJ_A_NOVA400_2","DNA GYRASE SUBUNIT B","4m18","PULMONARY SURFACTANT-ASSOCIATED PROTEIN D","Homo sapiens",3,"ASN A 341;PHE A 292;VAL A 343","MAN A 406 ( 2.6A);None;MAN A 406 ( 4.7A)","0.60A","1kijA-4m18A:undetectable","1kijA-4m18A:17.28"],["3HCR_A_CHDA424_0","FERROCHELATASE, MITOCHONDRIAL","4m18","PULMONARY SURFACTANT-ASSOCIATED PROTEIN D","Homo sapiens",4,"LEU A 268;ARG A 349;SER A 298;GLY A 346","None;MAN A 407 (-3.9A);None;None","1.16A","3hcrA-4m18A:undetectable","3hcrA-4m18A:18.36"],["3HCR_B_CHDB924_0","FERROCHELATASE, MITOCHONDRIAL","4m18","PULMONARY SURFACTANT-ASSOCIATED PROTEIN D","Homo sapiens",4,"LEU A 268;ARG A 349;SER A 298;GLY A 346","None;MAN A 407 (-3.9A);None;None","1.05A","3hcrB-4m18A:undetectable","3hcrB-4m18A:18.36"],["4MDB_A_RLTA401_1","MARINER MOS1 TRANSPOSASE","4m18","PULMONARY SURFACTANT-ASSOCIATED PROTEIN D","Homo sapiens",4,"ASP A 297;ASN A 323;ALA A 325;ASP A 330"," CA A 402 (-2.2A);MAN A 406 ( 2.6A);MAN A 405 ( 3.7A); CA A 403 ( 2.2A)","1.06A","4mdbA-4m18A:undetectable","4mdbA-4m18A:20.60"]]