SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4m1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 7 ARG A 132
ILE A 167
TYR A 123
GLY A 117
 None
 0.93A 11gsA-4m1bA:
undetectable		 11gsA-4m1bA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 6 LEU A 145
ILE A 106
ASP A 101
PRO A 100
 None
 1.14A 1ditH-4m1bA:
undetectable
1ditP-4m1bA:
undetectable		 1ditH-4m1bA:
21.51
1ditP-4m1bA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 10 LEU A 209
ALA A 221
VAL A 207
LEU A 229
GLN A 236
 None
 1.22A 1rlbE-4m1bA:
undetectable		 1rlbE-4m1bA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 8 ARG A 132
ILE A 167
TYR A 123
GLY A 117
 None
 0.96A 3n9jA-4m1bA:
undetectable		 3n9jA-4m1bA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		3 / 3 ILE A 206
VAL A 176
ARG A 154
 None
 0.73A 3p73A-4m1bA:
undetectable		 3p73A-4m1bA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLY A  52
THR A 246
ILE A 243
GLN A 236
ILE A 237
 None
 1.23A 4zvmA-4m1bA:
undetectable
4zvmB-4m1bA:
undetectable		 4zvmA-4m1bA:
20.50
4zvmB-4m1bA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 8 LEU A 222
ILE A  75
ALA A 211
PHE A  89
 None
 1.01A 5m0oC-4m1bA:
undetectable		 5m0oC-4m1bA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4m1b POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 8 ASP A  64
TRP A 178
TRP A 185
HIS A 210
 None
 0.41A 5nekD-4m1bA:
22.6		 5nekD-4m1bA:
20.90